重症肌无力合并胸腺瘤的外科治疗进展  

Advances in Surgical Treatment of Myasthenia Gravis with Thymoma

作　　者：袁博文 吴蕊玥 梁秋豪 王晨晗 马敏杰[2,3,4] 韩彪 YUAN Bowen;WU Ruiyue;LIANG Qiuhao;WANG Chenhan;MA Minjie;HAN Biao(the First School of Clinical Medicine of Lanzhou University,Lanzhou 730000,China;Department of Thoracic Surgery,the First Hospital of Lanzhou University,Lanzhou 730000,China;Gansu International Science and Technology Cooperation Base of Research and Development and Application of Key Technologies in Thoracic Surgery,Lanzhou 730000,China;Gansu Provincial Medical Quality Control Center of Thoracic Surgery,Lanzhou 730000,China)

机构地区：[1]兰州大学第一临床医学院,兰州730000 [2]兰州大学第一医院胸外科,兰州730000 [3]胸外科关键技术研发与应用专业甘肃省国际科技合作基地,兰州730000 [4]甘肃省胸外科医疗质量控制中心,兰州730000

出　　处：《医学综述》2023年第8期1552-1556,共5页Medical Recapitulate

基　　金：甘肃省科技计划项目(21JR1RA107,21JR1RA118)。

摘　　要：重症肌无力(MG)患者常合并胸腺肿瘤,胸腺肿瘤可通过产生病理性抗体引发患者出现肌无力。单一内科对症治疗并不能有效治愈MG,外科手术切除肿瘤可延长患者的生存期,已成为目前MG合并胸腺瘤患者的首选治疗方案。目前常规的外科手术方式主要包括开胸手术、胸腔镜辅助切除手术、达芬奇机器人辅助切除手术以及射频消融术等。胸腺瘤是否完整切除是患者术后肌无力复发的重要评估因素,临床医师应于术前充分评估,尽可能实施胸腺扩大切除术。未来深入研究外科手术在MG合并胸腺瘤患者中的应用价值,可以为患者的治疗提供新思路。Myasthenia gravis(MG)patients are often associated with thymic tumors,which produce pathological antibodies and then cause symptoms of myasthenia.Single symptomatic medical treatment cannot effectively cure the disease,while tumor resection can improve the long-term survival of the patients and has become the first choice for standardized treatment of MG complicated with thymoma.At present,conventional surgical methods mainly include thoracotomy,thoracoscopic-assisted resection,Da Vinci robot-assisted resection,and radiofrequency ablation.The complete resection of thymoma is an important evaluation factor for postoperative myasthenia recurrence.Therefore,clinicians should perform extended thymectomy as much as possible based on sufficient preoperative assessment.In the future,further study of the application value of surgery in MG patients with thymoma can provide new ideas for the treatment.

关 键 词：重症肌无力 胸腺瘤 外科术式 

分 类 号：R615[医药卫生—外科学]