阳江地区儿童变应性鼻炎患者过敏原筛查结果特征分析研究  

Analysis and Characteristics of Allergen Screening Results in Pediatric Allergic Rhinitis Patients in Yangjiang Region

作　　者：罗美方 刘立文 吴珠妹 LUO Meifang;LIU Liwen;WU Zhumei(Department of Clinical Laboratory,the Third People's Hospital of Yangjiang,Yangjiang Guangdong 529500,China;Department of Internal Medicine,the Third People's Hospital of Yangjiang,Yangjiang Guangdong 529500,China)

机构地区：[1]阳江市第三人民医院检验科,广东阳江529500 [2]阳江市第三人民医院内科,广东阳江529500

出　　处：《中国卫生标准管理》2023年第20期29-33,共5页China Health Standard Management

基　　金：阳江市卫生健康局科技计划项目(阳卫健2022007)。

摘　　要：目的调查分析阳江地区儿童变应性鼻炎患儿过敏原筛查结果特征。方法选取2022年8月—2023年5月于阳江市第三人民医院就诊的500例变应性鼻炎患儿作为研究对象。根据年龄分为2~9岁组(302例)和10~17岁组(198例);依据性别分为男童组(290例)和女童组(210例);根据居住地分为城市组(250)和农村组(250例)。通过血清变应原特异性IgE(specific IgE,sIgE)检测,分析总结阳江地区变应性鼻炎患儿过敏原筛查结果特征。结果500例变应性鼻炎患儿sIgE阳性420例(84.00%),单纯性吸入性变应原阳性205例(48.81%),单纯性食入性变应原阳性63例(15.00%),吸入性和食物双重阳性152例(36.19%)。农村患儿sIgE阳性144例(34.28%),城市患儿sIgE阳性276例(65.71%);不同年龄组患儿柳树、猫毛、狗毛、点青霉、分枝孢霉、牛肉、鳕鱼、虾及菠萝阳性比例比较,差异无统计学意义(P>0.05);2~9岁组豚草、艾蒿、尘螨及蟑螂阳性比例低于10~17岁组(P<0.05);2~9岁组鸡蛋白、牛奶阳性比例高于10~17岁组患儿(P<0.05);不同性别组患儿豚草、艾蒿、尘螨、蟑螂、猫毛、点青霉、分枝孢霉、鸡蛋白、牛奶、牛肉、鳕鱼、虾及菠萝阳性比例比较,差异无统计学意义(P>0.05);男童组柳树阳性比例低于女童组(P<0.05),男童组狗毛阳性比例高于女童组(P<0.05);城市与农村组患儿柳树、豚草、艾蒿、蟑螂、点青霉、分枝孢霉、鸡蛋白、牛奶、牛肉、鳕鱼及菠萝阳性比例比较,差异无统计学意义(P>0.05);城市组尘螨、猫毛、狗毛及虾阳性比例高于农村组(P<0.05);2~9岁组、10~17岁组患儿单一变应原、双重变应原、三重变应原、四重变应原及五重变应原阳性比例比较,差异无统计学意义(P>0.05)。结论阳江地区城市患儿sIgE阳性比例高于农村,城市患儿吸入性变应原以尘螨、猫毛、狗毛、点青霉为主,农村吸入性变应原以尘螨、点青霉、分枝孢霉为主;2~9岁组患儿吸�Objective To investigate and analyze the results of allergen screening in children with allergic rhinitis in Yangjiang region.Methods A total of 500 children with allergic rhinitis treated in the Third People's Hospital of Yangjiang from August 2022 to May 2023 were selected as the study objects.They were divided into 2 to 9 years old group(302 cases)and 10 to 17 years old group(198 cases).They were divided into male group(290 cases)and female group(210 cases)according to sex.They were divided into urban group(250 cases)and rural group(250 cases).Through the detection of specific IgE(sIgE)in serum,the characteristics of allergen screening in children with allergic rhinitis in Yangjiang region were analyzed and summarized.Results Among the 500 children with allergic rhinitis,420 cases(84.00%)were sIgE positive,205 cases(48.81%)were simple aspiration allergen positive,63 cases(15.00%)were simple ingestion allergen positive,and 152 cases(36.19%)were both aspiration and food positive.There were 144 cases(34.28%)sIgE positive cases in rural children and 276 cases(65.71%)sIgE positive cases in urban children.There was no significant difference in the positive proportion of willow,cat hair,dog hair,penicillium point,mycospora,beef,cod,shrimp and pineapple among children in different age groups(P>0.05).The positive proportion of ragweed,mugwort,dust mite and cockroach in 2 to 9 years old group was lower than that in 10 to 17 years old group(P<0.05).The proportion of egg white and milk positive in 2 to 9 years old group was higher than that in 10 to 17 years old group(P<0.05).There was no significant difference in the positive proportion of ragweed,artemisia mugwort,dust mites,cockroach,cat hair,penicillium punctata,mycospora,egg white,milk,beef,cod,shrimp and pineapple among different gender groups(P>0.05).The proportion of willow positive in boy group was lower than that in girl group(P<0.05),and the proportion of dog hair positive in boy group was higher than that in girl group(P<0.05).There was no significant differen

关 键 词：阳江地区 儿童变应性鼻炎 过敏原筛查 吸入性变应原 食入性应原 单一变应原 

分 类 号：R758[医药卫生—皮肤病学与性病学]