扩大标准供者器官受者权益保护的伦理建设  

Ethical construction of recipients’rights and interests protection in organ transplantation from expanded criteria donors

作　　者：聂峰 孙煦勇 廖吉祥 李壮江 Nie Feng;Sun Xuyong;Liao Jixiang;Li Zhuangjiang(Department of Pathology,the 923th Hospital of the Joint Service Support Force of the People's Liberation Army of China,Nanning 530021,China;不详)

机构地区：[1]中国人民解放军联勤保障部队第九二三医院病理科,南宁530021 [2]中国人民解放军联勤保障部队第九二三医院器官移植科,南宁530021 [3]广西医科大学第二附属医院器官移植科

出　　处：《器官移植》2023年第6期878-883,共6页Organ Transplantation

基　　金：广西卫生健康委员会科研课题(Z-A20221017、Z-A20231085)。

摘　　要：在移植器官严重短缺和公民逝世后器官捐献成为我国移植器官主要来源的背景下,扩大标准供者(ECD)器官已广泛应用于临床,但ECD存在基础疾病、高龄、外伤、休克或感染等情况,供器官质量会受到不同程度的影响,是影响移植疗效的重要因素之一。接受ECD器官移植受者也将承担ECD器官带来的额外风险和疗效的不确定性,需要重视受者权益保护。本文从ECD器官移植在受者保护方面面临的伦理问题、目前器官伦理委员会伦理审查上存在的不足进行综述,探讨器官移植受者权益的伦理审查机构与制度建设的建议,以期为促进ECD器官移植发展提供参考。Under the background of severe shortage of donor organs and organ donation after citizen's death becoming the main source of donor organs in China,expanded criteria donor(ECD)has been widely applied in clinical practice.However,ECD has the disadvantages of basic diseases,old age,trauma,shock or infection,which will affect the quality of donor organs to varying degrees and become one of critical factors affecting clinical efficacy of organ transplantation.The recipients of ECD organ transplantation will also bear the additional risk and uncertainty of efficacy brought by ECD organs.Hence,it is necessary to pay attention to the protection of the recipients’rights and interests.In this article,ethical issues faced by ECD organ transplantation in recipient protection and the shortcomings in the ethical review of organ ethics committee were reviewed,and suggestions on the ethical review institution and system construction of the rights and interests of organ transplantation recipients were elucidated,aiming to provide reference for promoting the advancement of ECD organ transplantation.

关 键 词：器官移植 器官短缺 公民逝世后器官捐献 扩大标准供者 权益保护 伦理审查 伦理建设 伦理委员会 

分 类 号：R617[医药卫生—外科学] R-052[医药卫生—临床医学]