独活属植物香豆素类化合物及其生物活性研究进展  

Coumarin Compounds of Genus Heracleum L.and Their Bioactivity:A Review

作　　者：潘妍[1] 范丽莉 孙海霞 孙阎[1] 李思凝 PAN Yan;FAN Lili;SUN Haixia;SUN Yan;LI Sining(College of Modern Agriculture and Ecology,Heilongjiang University,Harbin 150080;Center for Agricultural Technology,Northeast Institute of Geography and Agroecology,Chinese Academy of Sciences,Harbin 150081;American University of the Caribbean,School of Medicine,Pembroke Pines 33027,America)

机构地区：[1]黑龙江大学现代农业与生态环境学院,哈尔滨150080 [2]中国科学院东北地理与农业生态研究所农业技术中心,哈尔滨150081 [3]美国加勒比大学医学院,美国彭布罗克派恩斯33027

出　　处：《中国农学通报》2023年第29期14-23,共10页Chinese Agricultural Science Bulletin

基　　金：黑龙江省自然科学基金项目优秀青年类“兴安独活营养与重要生物活性物质积累及分布规律研究”(YQ2020C028);国家科技基础资源调查专项课题“完达山-张广才岭林区天然林野生经济植物种质资源调查”(2019FY100503)。

摘　　要：为独活属植物中香豆素类化合物的深入研究及利用提供参考,总结了独活属植物中已鉴定的香豆素类化合物的种类及其化学结构,归纳了其在抗菌、抗氧化、抗细胞增殖、抗炎、毒性等方面的研究进展,比较分析了国内外相关研究差异。揭示了独活属植物中香豆素类化合物的多样性及其食药用价值,提出其在药物开发过程中存在功能研究不够深入、系统,活性成分不明确等问题。建议加强毒性和药效研究,促进独活属植物作为食药用植物资源的开发和利用。To provide a reference for the in-depth research and utilization of coumarin compounds in the genus Heracleum,this review summarized the types and chemical structures of the identified coumarin compounds in the genus Heracleum,concluded the research progress in aspects of anti-bacteria,anti-oxidation,anti-cell proliferation,anti-inflammation,toxicity,etc,and comparatively analyzed the difference between relevant domestic and foreign researches.It revealed the diversity of coumarin compounds in the genus Heracleum and their values in medical and food industries.It proposed during the drug development process,there are problems,such as the research in its function is not deep or systemic enough,active ingredients are unclear,etc.It suggested fortifying research on its toxicity and efficacy and promoting the development and utilization of the genus Heracleum as a plant resource for foods and medicine.

关 键 词：独活属 香豆素类化合物 生物活性 植物利用 

分 类 号：S58[农业科学—作物学]