维持性血液透析患者心血管相关并发症致病机制研究进展  

Research Progress in Pathogenesis of Cardiovascular-related Complications in Maintenance Hemodialysis Patients

作　　者：宋娜 何秀丽 SONG Na;HE Xiuli(Department of Nephrology,Tai′an 88 Hospital,Tai′an 271000,China;Department of Nephrology and Rheumatology,Tai′an Municipal Hospital,Tai′an 271000,China)

机构地区：[1]泰安八十八医院肾内科,山东泰安271000 [2]泰安市立医院肾内与风湿免疫科,山东泰安271000

出　　处：《医学综述》2023年第15期3032-3036,共5页Medical Recapitulate

摘　　要：维持性血液透析(MHD)的目的在于替代肾衰竭丢失的部分功能(如清除代谢废物,调节水、电解质和酸碱平衡),是延长终末期肾病患者生命的有效方法。心血管相关并发症是导致MHD患者死亡的首要原因,且以透析高血压、心律失常、心力衰竭、心室肥厚、血管钙化最常见,而诱发MHD患者心血管相关并发症发生的危险因素主要包括慢性微炎症状态、高脂血症、高磷血症以及透析相关特异性危险因素等。因此,综合评估MHD患者心血管相关并发症并及时给予针对性干预措施,有助于降低MHD患者病死率。Maintenance hemodialysis(MHD)aims to replace some of the functions lost in renal failure(such as removal of metabolic waste,regulation of water,electrolytes,and acid-base balance)and is an effective way to prolong the life of patients with end-stage renal disease.Cardiovascular complications are the leading cause of death in patients with MHD,the most common of which are dialytic hypertension,arrhythmia,heart failure,ventricular hypertrophy,and vascular calcification.The risk factors for cardiovascular complications in MHD patients mainly include chronic microinflammatory state,hyperlipidemia,hyperphosphatemia and dialysis-related specific risk factors.Therefore,comprehensive assessment of cardiovascular complications in MHD patients and targeted measures can help to reduce the mortality of MHD patients.

关 键 词：维持性血液透析 心血管相关并发症 透析高血压 心律失常 心力衰竭 

分 类 号：R446.1[医药卫生—诊断学]