Detecting nanoparticles by“listening”  

作　　者：Haonan Chang Jun Zhang 

机构地区：[1]State Key Laboratory of Superlattices and Microstructures,Institute of Semiconductors,Chinese Academy of Sciences,Beijing 100083,China [2]Center of Materials Science and Optoelectronics Engineering,University of Chinese Academy of Sciences,Beijing 100049,China

出　　处：《Frontiers of physics》2023年第5期113-131,共19页物理学前沿（英文版）

基　　金：J.Z.acknowledges the National Key Research and Development Program of China(No.2017YFA0303401);CAS Interdisciplinary Innovation Team,the National Natural Science Foundation of China(No.12074371);the Strategic Priority Research Program of Chinese Academy of Sciences(No.XDB28000000).

摘　　要：In the macroscopic world,we can obtain some important information through the vibration of objects,that is,listening to the sound.Likewise,we can also get some information of the nanoparticles that we want to know by the means of“listening”in the microscopic world.In this review,we will introduce two sensing methods(cavity optomechanical sensing and surface-enhanced Raman scattering sensing)which can be used to detect the nanoparticles.The cavity optomechanical systems are mainly used to detect sub-gigahertz nanoparticle or cavity vibrations,while surface-enhanced Raman scattering is a well-known technique to detect molecular vibrations whose frequency generally exceeds terahertz.Therefore,the vibrational information of nanoparticles from low-frequency to high-frequency could be obtained by these two methods.The size of the viruses is at the nanoscale and we can regard it as a kind of nanoparticles.Rapid and ultrasensitive detection of the viruses is the key strategies to break the spread of the viruses in the community.Cavity optomechanical sensing enables rapid,ultrasensitive detection of nanoparticles through the interaction of light and mechanical oscillators and surface-enhanced Raman scattering is an attractive qualitatively analytical technique for chemical sensing and biomedical applications,which has been used to detect the SARS-CoV-2 infected.Hence,investigation in these two fields is of vital importance in preventing the spread of the virus from affecting human’s life and health.

关 键 词：ultrasensitive sensing cavity optomechanics surface-enhanced Raman scattering 

分 类 号：TB383.1[一般工业技术—材料科学与工程]