妊娠相关静脉血栓栓塞性疾病的诊疗与预防  

Diagnosis,Treatment and Prevention of Pregnancy associated Venous Thromboembolism Disease

作　　者：于秀章 汪月梅 张力 YU Xiuzhang;WANG Yuemei;ZHANG Li(Department of Obstetrics and Gynecology,West China Second University Hospital,Sichuan University/Key Laboratory of Birth Defects and Related Diseases of Women and Children,Ministry of Education,Chengdu 610041,China)

机构地区：[1]四川大学华西第二医院妇产科、出生缺陷与相关妇儿疾病教育部重点实验室,成都610041

出　　处：《医学综述》2022年第20期4070-4076,共7页Medical Recapitulate

摘　　要：妊娠期及产褥期静脉血栓栓塞性疾病(VTE)严重危害孕产妇的身心健康,且具有一定致死性。临床工作中应加强症状、体征监测,对疑似VTE患者合理选择影像学等进一步检查,减少漏诊、误诊。妊娠相关VTE的诊疗和预防需同时考虑孕产妇及其胎婴儿的安全。低分子肝素是妊娠期VTE首选抗凝药物,产后抗凝治疗至少应维持6周。妊娠相关VTE的预防需根据血栓形成风险不同进行分层管理,但目前国际指南的推荐尚未统一,国内亦无相关指南,因此,探索符合我国国情的妊娠相关VTE防治策略意义重大。Venous thromboembolic disease(VTE)during pregnancy and puerperium seriously endangers the physical and mental health of women,which has a certain degree of lethality.In clinical work,the monitoring of symptoms and signs should be strengthened,and further examinations such as imaging examinations should be reasonably selected for suspected VTE patients,to reduce missed diagnosis and misdiagnosis.The diagnosis,treatment and prevention of pregnancy associated VTE should consider the safety of maternal and their fetuses or infants.Low molecular weight heparin is the first choice of anticoagulant therapy during pregnancy,and postpartum anticoagulant therapy should be continued for at least 6 weeks.The prevention of pregnancy associated VTE needs to be managed hierarchically according to the risk of thrombosis,but the recommendations of international guidelines are not yet uniform,and there is no relevant guideline in China.It is of great significance to explore pregnancy associated VTE prevention and treatment strategies which accord with the actual situation of China.

关 键 词：静脉血栓栓塞性疾病 妊娠期 产褥期 低分子肝素 血栓防治 抗凝治疗 

分 类 号：R714.7[医药卫生—妇产科学]