环己胺合成研究进展  

Research progress in synthesis of cyclohexylamine

作　　者：张美华 钟齐锋 陈梦婷 刘迎新[1] ZHANG Meihua;ZHONG Qifeng;CHEN Mengting;LIU Yingxin(College of Pharmacy,Zhejiang University of Technology,Hangzhou 310014,China)

机构地区：[1]浙江工业大学药学院,浙江杭州310014

出　　处：《石油化工》2023年第10期1452-1460,共9页Petrochemical Technology

基　　金：浙江省自然科学基金项目(LY23B060006,LY18B060016)。

摘　　要：根据所用原料的不同,综述了国内外环己胺合成方法的研究进展,着重介绍了各个方法所使用的催化体系、反应机理,简单介绍了催化剂的结构-反应性的关系、稳定性和普适性。其中,酚类还原胺化法具有原料可再生、原子经济性高等优点,而更具优势。展望了环己胺合成的发展前景,指出今后的发展方向是将生物质一步转化为环己胺。The research progress in various synthesis methods of cyclohexylamine at home and abroad is systematically introduced according to the different raw materials used.The catalytic system and reaction mechanism are emphasized,and the structure-reactivity relationship,stability and universality of the catalysts are briefly introduced.Among them,the phenol reductive amination method has the advantages of renewable starting materials and high atomic economy.Finally,the development trend of cyclohexylamine synthesis is prospected.It is pointed out that the development direction is one-step conversion of biomass to cyclohexylamine.

关 键 词：环己胺 合成方法 催化 还原胺化 生物质 

分 类 号：TQ226.31[化学工程—有机化工]