The modifying influence of HLA classⅡDQB1^(*)06:02 on the Streptococcus and clinical phenotype correlation among anti-Ro+mothers of children with neonatal lupus  

作　　者：Robert M.Clancy Carla J.Guthridge Miranda C.Marion Joel Guthridge Timothy D.Howard Peter M.Izmirly Mala Masson Jill P.Buyon Judith A.James Carl D.Langefeld 

机构地区：[1]Department of Medicine,Division of Rheumatology,NYU Grossman School of Medicine,New York,NY 10016,USA [2]Arthritis and Clinical Immunology,Oklahoma Medical Research Foundation,Oklahoma City,OK 73104,USA [3]Department of Biostatistics and Data Science,Wake Forest School of Medicine,Winstone Salem,NC 27101,USA [4]Center for Precision Medicine,Wake Forest School of Medicine,WinstoneSalem,NC 27101,USA [5]Department of Biochemistry,Wake Forest School of Medicine,WinstoneSalem,NC 27101,USA

出　　处：《Genes & Diseases》2023年第4期1169-1171,共3页基因与疾病（英文）

基　　金：supported by the National Institutes of Health,Bethesda,MD[No.5P50 AR070591(J.P.B.),5R21 AR071106(J.P.B.and C.D.L.),AR-4-2220(J.P.B.),P30AR073750(JAJ),UM1AI144292(JAJ)].

摘　　要：The genus Streptococcus,a gram-positive bacterium,con-tains species associated with immune activation at morbid outcomes,including scarlet fever,endocarditis,meningitis,and rheumatic fever.In both stool and saliva,there is a pos-itive correlation between Streptococcus abundance and Sjogren’s syndrome(SS)and systemic lupus erythematosus(SLE).

关 键 词：LUPUS mother FEVER STREPTOCOCCUS 

分 类 号：R59[医药卫生—内科学]