γ-谷氨酰转移酶与动脉粥样硬化相关性研究进展  

Research progress on the relationship between gamma-glutamyltransferase and atherosclerosis

作　　者：吴璇(综述) 唐乙月 陈明星(审校) WU Xuan;TANG Yiyue;CHEN Mingxing(Graduate School of Dalian Medical University,Dalian,Liaoning 116000,China;Department of Cardiology,Subei People′s Hospital,Yangzhou,Jiangsu 225000,China)

机构地区：[1]大连医科大学研究生院,辽宁大连116000 [2]苏北人民医院心内科,江苏扬州225000

出　　处：《现代医药卫生》2023年第21期3714-3718,3724,共6页Journal of Modern Medicine & Health

基　　金：国家自然科学基金项目(82100429);江苏省卫生健康委员会面上项目(M2021040)。

摘　　要：γ-谷氨酰转移酶(GGT)是肝酶谱检测指标之一,其检测成本低而灵敏度较高,因而被广泛用于临床检测肝胆疾病及酒精蓄积。近年来,GGT已被引入作为新的氧化应激血清标志物,同时,也有研究表明,GGT水平升高预示心血管疾病发生率增加,可将GGT视为检测动脉粥样硬化的新型血清学指标。Gamma-glutamyl transferase(GGT)is one of the indicators of liver zymogram detection.Its detection cost is low and sensitivity is high,so it is widely used in clinical practice to detect hepatobiliary diseases and alcohol accumulation.In recent years,GGT has been introduced as a new serum marker of oxidative stress.At the same time,some studies have shown that the increase of GGT level indicates an increase in the incidence of cardiovascular disease,which can be regarded as a new serological indicator for detecting atherosclerosis.

关 键 词：Γ-谷氨酰转移酶 动脉粥样硬化 冠心病 氧化性应激 综述 

分 类 号：R543.5[医药卫生—心血管疾病] R446.11[医药卫生—内科学]