卡托普利舌下含服和硝酸甘油静脉滴注在急诊高血压治疗中的效果分析  

Analysis of the efficacy of sublingual captopril and intravenous nitroglycerin infusion in the treatment of hypertension in the emergency department

作　　者：卓小婷 ZHUO Xiaoting(Department of Emergency,Yangzhou Hospital of TCM,Jiangsu,Yangzhou 225000,China)

机构地区：[1]江苏省扬州市中医院急诊科,江苏扬州225000

出　　处：《中国医药科学》2023年第20期54-57,共4页China Medicine And Pharmacy

摘　　要：目的分析卡托普利舌下含服和硝酸甘油静脉滴注在急诊高血压治疗中的效果。方法选取扬州市中医院2019年1月至2021年12月收治的急诊高血压患者60例,根据随机数表法分为两组,每组各30例。对照组行硝酸甘油静脉滴注治疗,观察组行卡托普利舌下含服和硝酸甘油静脉滴注治疗。比较两组患者收缩压稳定降低至正常范围时间,舒张压稳定降低至正常范围时间,治疗前后患者舒张压、收缩压、心室率,总有效率及不良反应。结果观察组收缩压稳定降低至正常范围时间、舒张压稳定降低至正常范围时间短于对照组,观察组总有效率高于对照组,差异均有统计学意义(P<0.05)。两组治疗过程中未见不良反应,差异无统计学意义(P>0.05)。治疗前两组患者舒张压、收缩压、心室率比较,差异无统计学意义(P>0.05),而治疗后两组舒张压、收缩压、心室率均改善,且观察组舒张压、收缩压、心室率显著低于对照组,差异有统计学意义(P<0.05)。结论卡托普利舌下含服和硝酸甘油静脉滴注对于急诊高血压的治疗效果优于硝酸甘油静脉滴注单一治疗,更有利于降低血压和心室率,且安全性高。Objective To analyze the efficacy of sublingual captopril and intravenous nitroglycerin infusion in the treatment of hypertension in the emergency department.Methods A total of 60 hypertensive patients in the Department of Emergency,Yangzhou Hospital of TCM from January 2019 to December 2021 were selected.The patients were divided into two groups with 30 patients in each group using the random number table method.The control group received intravenous nitroglycerin infusion,while the observation group received sublingual captopril and intravenous nitroglycerin infusion.The time when systolic blood pressure stabilized to the normal range,the time when diastolic blood pressure stabilized to the normal range,and the diastolic blood pressure,ventricular rate,total effective rate,and adverse reactions of the two groups before and after treatment were compared.Results The time for stable reduction of systolic blood pressure to the normal range and the time for stable reduction of diastolic blood pressure to the normal range in the observation group were shorter than those in the control group.The total effective rate in the observation group was higher than that in the control group,with statistically significant differences(P<0.05).There were no adverse reactions during the treatment between the two groups,with no statistically significant difference(P>0.05).There were no stat istically significant differences in diastolic blood pressure,systolic blood pressure,and ventricular rate before treatment between the two groups(P>0.05).However,diastolic blood pressure,systolic blood pressure,and ventricular rate after treatment were improved in both groups,and the observation group had significantly lower diastolic blood pressure,systolic blood pressure,and ventricular rate than the control group,with statistically significant differences(P<0.05).Conclusion The efficacy of sublingual captopril combined with intravenous nitroglycerin infusion in the treatment of hypertension in the emergency department is better than that of

关 键 词：卡托普利 硝酸甘油 急诊高血压 心室率 

分 类 号：R544.1[医药卫生—心血管疾病]