肺功能成像在新型冠状病毒肺炎急性及康复期病变的研究进展  

Research progress of pulmonary functional imaging in acute and convalescent lesions of COVID-19

作　　者：刘晓玉 单飞[1] LIU Xiao-yu;SHAN Fei(Department of Radiology,Shanghai Public Health Clinical Center,Fudan University,Shanghai 201508,China)

机构地区：[1]上海市(复旦大学附属)公共卫生临床中心放射科,上海201508

出　　处：《中国临床医学》2023年第4期730-735,共6页Chinese Journal of Clinical Medicine

基　　金：科技创新2030—“新一代人工智能”重大项目(2021ZD0111103).

摘　　要：截至2022年11月4日,新型冠状病毒肺炎(coronavirus disease 2019,COVID-19)确诊病例超过6.28亿,死亡人数超过657万。肺是COVID-19最常累及的器官,主要表现为COVID-19肺炎、肺血栓栓塞等急性病变及康复期COVID-19相关小气道病变、肺间质纤维化。肺功能成像使用影像学成像技术对肺功能进行区域性可视化量化评估,并额外提供常规肺功能检查未涉及的区域分布及定位信息。为全面了解肺功能成像技术在COVID-19患者中的应用价值,本文归纳总结CT、MRI及核医学成像技术在COVID-19急性及康复期病变早期识别、诊断及随访中的初步应用,并展望各种成像模态及相关技术在未来更广泛的应用。During the coronavirus disease 2019(COVID-19)pandemic,more than 628 million people were diagnosed and more than 6.57 million died.The lung is the most frequently involved organ of COVID-19,which is mainly manifested as COVID-19 pneumonia and pulmonary thromboembolism in acute phase and COVID-19 related small airway disease and pulmonary interstitial fibrosis in convalescent phase.Pulmonary functional imaging uses imaging techniques for regional visual and quantitative assessment of lung function,providing additional regional distribution and location information,which cannot be provided by routine pulmonary function test.In order to fully understand the application value of pulmonary functional imaging in patients with COVID-19,this review summarizes the preliminary clinical application of CT,MRI and nuclear medicine imaging techniques in the early screening,diagnosis,and follow-up of acute and convalescent lesions in COVID-19,and looks forward to the wider application of various imaging modalities and related technologies in the future.

关 键 词：新型冠状病毒肺炎 功能成像 肺血栓栓塞 小气道病变 肺间质纤维化 

分 类 号：R563[医药卫生—呼吸系统]