尿毒症合并急性呼吸窘迫综合征气管插管拔除后不同氧疗方式的疗效分析  

The Efficacy of Different Oxygen Therapy Modalities after Extubation of Tracheal Tube in Uremia Combined with Acute Respiratory Distress syndrome

作　　者：韦亚军 徐丹 WEI Yajun;XU Dan(Sihong County First People's Hospital,Suqian 223900,China;Changshu First People's Hospital,Changshu 215500,China)

机构地区：[1]泗洪县第一人民医院,江苏宿迁223900 [2]常熟市第一人民医院,江苏常熟215500

出　　处：《中国医药指南》2023年第31期75-77,共3页Guide of China Medicine

摘　　要：目的分析尿毒症合并急性呼吸窘迫综合征气管插管拔除后不同氧疗方式的疗效。方法选择2021年1月至2022年12月泗洪县第一人民医院接诊的50例尿毒症合并急性呼吸窘迫综合征患者为研究对象,随机分为两组,对照组给与面罩吸氧,观察组给与经鼻高流量湿化氧疗。对比两组治疗前后的PO_(2)、PCO_(2)、心率和平均动脉压。结果两组患者治疗前PO_(2)、PCO_(2)、心率及平均动脉压比较,差异均无统计学意义。治疗后,观察组PO_(2)较对照组高[(95.68±8.01)mm Hg vs.(82.98±7.06)mm Hg,P=0.027],PCO_(2)较对照组低[(53.62±3.59)mm Hg vs.(62.81±3.44)mm Hg,P=0.031],心率较对照组低[(88.53±9.06)次/分vs.(96.38±9.44)次/分,P=0.022],平均动脉压较对照组低[(118.73±8.05)mm Hg vs.(131.46±8.77)mm Hg,P=0.014]。结论经鼻高流量湿化氧疗较面罩吸氧对尿毒症合并急性呼吸窘迫综合征患者有更好的疗效。Objective To analyze the efficacy of different oxygen therapy modalities after extubation of tracheal intubation in uremia combined with acute respiratory distress syndrome.Methods A total of 50 patients with uremia combined with acute respiratory distress syndrome received by the First People's Hospital of Sihong County from January 2021 to December 2022 were selected as the study subjects and were randomly divided into two groups,the control group was given mask oxygen intake,and the observation group was given transnasal high-flow humidified oxygen therapy.PO_(2),PCO_(2),heart rate and mean arterial pressure were compared between the two groups before and after treatment.Results Comparison of PO_(2),PCO_(2),heart rate and mean arterial pressure between the two groups before treatment showed no statistically significant difference.After treatment,PO_(2)in the observation group was higher than that in the control group[(95.68±8.01)mm Hg vs.(82.98±7.06)mm Hg,P=0.027],PCO_(2)was lower than that in the control group[(53.62±3.59)mm Hg vs.(62.81±3.44)mm Hg,P=0.031],and heart rate was lower than that in the control group[(88.53±9.06)beats/min vs.(96.38±9.44)beats/min,P=0.022],and lower mean arterial pressure than the control group[(118.73±8.05)mm Hg vs.(131.46±8.77)mm Hg,P=0.014].Conclusions Transnasal high-flow humidified oxygen therapy has better efficacy than face mask oxygen for patients with uremia combined with acute respiratory distress syndrome.

关 键 词：尿毒症 急性呼吸窘迫综合征 氧疗 预后 

分 类 号：R459.6[医药卫生—治疗学]