牛源大肠杆菌耐药性研究进展  

Progress on the Antibiotics Resistance of Escheichia coli from Bovine

作　　者：张玉杰 王晓旭[1] 徐锋[1] 沈莉萍[1] 葛菲菲[1] 刘健[1] 唐聪圣 王建[1] ZHANG Yu-jie;WANG Xiao-xu;XU Feng;SHEN Li-ping;GE Fei-fei;LIU Jian;TANG Cong-sheng;WANG Jian(Shanghai Animal Disease Control Center,Shanghai 201103)

机构地区：[1]上海市动物疫病预防控制中心,上海201103

出　　处：《中国奶牛》2023年第10期29-36,共8页China Dairy Cattle

基　　金：上海市科技兴农重点攻关项目(2020-02-08-00-08-F01489);嘉定区自然科学研究课题(JDKW-2021-0006)。

摘　　要：牛源致病性大肠杆菌是导致牛细菌性疾病的重要病原体之一,抗菌药是治疗及预防牛大肠杆菌病的重要手段,然而在养殖过程中,长期且不合理的使用抗菌药物,导致大肠杆菌耐药问题频发,且耐药性具有通过人与动物的直接接触或借助食物链将耐药基因从动物传播给人类的可能,严重威胁人类健康及公共卫生安全。本文根据近几年国内外关于牛源大肠杆菌耐药性基因的研究报道,对大肠杆菌耐药机制、耐药基因检出率及耐药表型进行综述,以期为大肠杆菌耐药性的研究提供参考。Pathogenic Escherichia coli(E coli)from Bovine is one of the important pathogens that cause bovine bacterial diseases.Antibiotics are important for the treatment and prevention of bovine colibacillosis.However,long-term and unreasonable use of antibiotics in the breeding process leads to frequent drug resistance of E.coli,and the drug resistance may be transmitted from animals to humans through direct contact between humans and animals or through the food chain,serious threat to human health and public health security.According to the recent reports on the resistance genes of bovine E.coli at home and abroad,the drug-resistance mechanism,drug-resistance genes and drug-resistance phenotypes of E.coli were reviewed,in order to provide reference for the study of E.coli resistance.

关 键 词：牛 大肠杆菌 耐药机制 耐药表型 耐药基因 

分 类 号：S858.23[农业科学—临床兽医学]