21世纪全球视域下的柴胡热点前沿知识图谱构建及可视化分析  

Knowledge graph construction and visualization analysis of hotspots and frontiers of Bupleuri Radix in 21st century global perspective

作　　者：陈奕旸 刘超[1] 刘娟娟[1] 张佳玲 王良才 席少阳 黄璐琦[2] 晋玲[1,3,4,5] CHEN Yi-yang;LIU Chao;LIU Juan-juan;ZHANG Jia-ling;WANG Liang-cai;XI Shao-yang;HUANG Lu-qi;JIN Ling(Gansu University of Traditional Chinese Medicine,Lanzhou 730000,China;TCM Resource Center,China Academy of Chinese Medical Sciences,Beijing 100700,China;Long-yao Industry Innovation Research Institute,Lanzhou 730000,China;Gansu Engineering Research Center for Evaluation,Protection and Utilization of Rare Traditional Chinese Medicine Resources,Lanzhou 730000,China;Northwest Chinese-Tibetan Medicine Collaborative Innovation Center,Lanzhou 730000,China)

机构地区：[1]甘肃中医药大学,甘肃兰州730000 [2]中国中医科学院中药资源中心,北京100700 [3]陇药产业创新研究院,甘肃兰州730000 [4]甘肃省珍稀中药资源评价与保护利用工程研究中心,甘肃兰州730000 [5]西北中藏药协同创新中心,甘肃兰州730000

出　　处：《中草药》2023年第20期6763-6776,共14页Chinese Traditional and Herbal Drugs

基　　金：中国工程院战略研究与咨询项目(GS2021ZDA06);道地药材生态种植及质量保障项目(国中医药科技[2020]153号);财政部和农业农村部:国家现代农业产业技术体系资助(CARS-21);甘肃省珍稀中药资源评价与保护利用工程研究中心开放基金(GSZXZY202203)。

摘　　要：目的通过对近20年柴胡相关研究的文献分析,探析柴胡研究领域的相关热点与前沿。方法以中国知网(CNKI)、万方(Wanfang)、维普(VIP)以及Web of Science(WOS)等国内外数据库为数据源,运用COOC对数据进行处理筛选,运用VOSviewer对文献年度发文量、机构、关键词、作者等内容进行分析,绘制可视化图谱。结果共纳入中文文献64919篇,英文文献200篇。文献数量整体呈增长趋势;研究机构主要以中南大学和北京中医药大学为代表;中、英文关键词显示,柴胡的主要研究方向为柴胡皂苷、柴胡疏肝散、药动学、小柴胡汤等;目前柴胡的研究热点主要为柴胡皂苷、中医药疗效、临床应用以及柴胡的相关方剂等。结论柴胡研究目前处于快速发展阶段,该领域的最新进展主要集中于对其临床疗效、药理作用的靶点、信号通路以及基因层面的深入研究等。Objective To analyze the relevant hot spots and frontiers in the research field of Chaihu(Bupleuri Radix)through the literature analysis of Bupleuri Radix related research in the past 20 years.Methods Using domestic and foreign databases such as CNKI,Wanfang,VIP and Web of science(WOS)as data sources,COOC was used to process and screen the data,and VOSviewer was saikosaponin,Chaihu Shugan San(柴胡疏肝散),pharmacokinetics,Xiaochaihu Decoction(小柴胡汤),etc.At present,the research focus of Bupleuri Radix mainly included saikosaponin,curative effect of traditional Chinese medicine,clinical application and relevant prescriptions of Bupleuri Radix.Conclusion The research of Bupleuri Radix was currently in a rapid development stage.The latest progress in this field mainly focuses on its clinical efficacy,pharmacological targets,signaling pathways and gene levels.

关 键 词：柴胡 文献计量学 研究热点 研究趋势 可视化分析 柴胡皂苷 柴胡疏肝散 小柴胡汤 

分 类 号：R28[医药卫生—中药学] G350[医药卫生—中医学]