Box-Behnken设计-响应面法优化蒲公英根产地初加工工艺  

Optimization of primary processing of Taraxacum mongolicum roots in origin by Box-Behnken design response surface method

作　　者：王建强 姜爽 唐姗[1] 李伟[1,2] WANG Jian-qiang;JIANG Shuang;TANG Shan;LI Wei(College of Chinese Medicinal Materials,Jilin Agricultural University,Changchun 130118,China;College of Life Sciences,Jilin Agricultural University,Changchun 130118,China)

机构地区：[1]吉林农业大学中药材学院,吉林长春130118 [2]吉林农业大学生命科学学院,吉林长春130118

出　　处：《中草药》2023年第19期6295-6304,共10页Chinese Traditional and Herbal Drugs

基　　金：吉林省科技发展计划(20210204041YY);吉林省科技发展计划(20200708067YY);吉林省教育厅科学技术研究项目(JJKH20210375KJ)。

摘　　要：目的通过多种评价指标,利用综合加权评分法以及Box-Behnken设计-响应面法(Box-Behnken design-response surface method,BBD-RSM)全面优化蒲公英Taraxacum mongolicum产地加工关键技术。方法蒲公英根的产地加工主要与切制前不同含水量、不同干燥方式及烘干温度、不同切制厚度3个因素密切相关。比较了蒲公英根在10种不同干燥方法、5种不同切制厚度下各类化学成分的变化。结果优选了蒲公英根产地初加工工艺最优参数为含水量70%,烘干温度50℃,切制厚度(13±2)mm。结论优化出的蒲公英根产地最佳工艺切实可行,工艺简便,可操作性强,进一步丰富蒲公英根质量评价标准,为蒲公英根产地初加工提供参考依据。Objective To optimize the key technologies of Pugongying(Taraxacum mongolicum)origin processing comprehensively through multiple evaluation indicators using a comprehensive weighted scoring method as well as the Box-Behnken design-response surface method(BBD-RSM).Methods The origin processing of T.mongolicum roots was closely related to three factors:different moisture contents before cutting,different drying methods and drying temperatures,and different cutting thicknesses.The changes in the chemical composition of T.mongolicum roots were compared for 10 different drying methods and five different cutting thicknesses.Results The optimal parameters for origin primary processing of T.mongolicum roots were optimized as 70%moisture content,50℃drying temperature,and(13±2)mm cutting thickness.Conclusion The optimized origin process of T.mongolicum roots is practical,simple and operable,which provide basis for the further origin process of T.mongolicum roots.

关 键 词：蒲公英根 芦丁 单咖啡酰酒石酸 绿原酸 咖啡酸 菊苣酸 齐墩果酸 Box-Behnken设计响应面法 产地加工 

分 类 号：R283.6[医药卫生—中药学]