终末期肿瘤患者口腔干燥症管理的证据总结  

Evidence summary for the management of xerostomia in patients with terminal cancer

作　　者：燕梦瑶 肖亚洲 夏婉婷 谌永毅 许湘华 YAN Mengyao;XIAO Yazhou;XIA Wanting;CHEN Yongyi;XU Xianghua(Xiang Ya Nursing School,Central South University,Changsha,410013,China)

机构地区：[1]中南大学湘雅护理学院,长沙市410013 [2]湖南省肿瘤医院/中南大学湘雅医学院附属肿瘤医院院办 [3]湖南省肿瘤医院/中南大学湘雅医学院附属肿瘤医院健康服务中心

出　　处：《中国护理管理》2023年第10期1539-1544,共6页Chinese Nursing Management

基　　金：2020年度湖南省科技厅重点研发项目(2020SK2121)。

摘　　要：目的:总结终末期肿瘤患者口腔干燥症管理的相关证据,为临床实践提供循证依据。方法:依据循证资源“6S”金字塔模型,自上而下依次检索数据库、相关网站中关于终末期肿瘤患者口腔干燥症管理的文献。检索时限为建库至2023年3月1日。由4名经循证护理系统培训的研究人员对纳入文献独立地进行质量评价和证据提取,并结合专家意见,汇总证据。结果:共纳入12篇文献,其中临床决策5篇,指南2篇,系统评价3篇,专家共识2篇。从口腔干燥症的管理原则、评估与筛查、非药物干预、药物干预4个类别总结了20条证据。结论:终末期肿瘤患者口腔干燥症管理的证据可以为医护人员有效管理患者口腔干燥及口腔健康相关问题提供循证依据,以适宜的、科学的、审慎的方法缓解患者的不适,提升安宁疗护服务质量。Objective:To summarize evidence on the management of xerostomia in patients with terminal cancer,and provide an evidence-based basis for clinical practice.Methods:Based on the"6S"pyramid model of evidence-based resources,the top-down search was conducted for articles on the management of xerostomia in patients with terminal cancer in databases and relevant websites.The retrieval time was from the establishment of database to March 1,2023.Quality evaluation and evidence extraction of the included literature were conducted independently by 4 researchers trained in evidence-based care systems,and we combined with specialists'advice to summarize the evidence.Results:A total of 12 articles were included,consisting of 5 clinical decisions,2 guidelines,3 systematic reviews and 2 expert consensus.Totally 20 pieces of evidence were summarized from 4 aspects of management principles,assessment and screening,non-pharmacological interventions,and pharmacological interventions for xerostomia.Conclusion:The summary of evidence on the management of xerostomia in patients with terminal cancer can provide an evidence-based basis for healthcare professionals to effectively manage patients'xerostomia and oral health-related problems in an appropriate,scientific and prudent way to alleviate patients'discomfort,and improve the quality of hospice services.

关 键 词：终末期 肿瘤 口腔干燥症 证据总结 循证护理 

分 类 号：R47[医药卫生—护理学] R197[医药卫生—临床医学]