胸腔镜与开胸手术治疗肺隔离症疗效及安全性的研究:系统评价与Meta分析  

The efficacy and safety of thoracoscopy and thoracotomy in the treatment of pulmonary sequestration:updated systematic evaluation and meta-analysis

作　　者：李犇 徐正哲[1] 蔡建辉[2] LI Ben;XU Zhengzhe;CAI Jianhui(Affiliated Hospital of Yanbian University,Yanji,Jilin Province,133000,Jilin;Jilin Medical University,Jilin City,Jilin Province,132013,China)

机构地区：[1]延边大学附属医院,吉林延吉133000 [2]吉林医药学院,吉林吉林132013

出　　处：《吉林医药学院学报》2023年第6期401-405,409,共6页Journal of Jilin Medical University

摘　　要：目的分析并探讨胸腔镜与开胸手术治疗肺隔离症的术后疗效及安全性。方法计算机检索KCI-Korean Journal Database、Pubmed、The Cochrane Library、EMbase、MEDLINE R、Wan Fang Date、Web of Science、中国知网数据库、维普数据库。搜索从建库到2022年10月20日公开发表的关于胸腔镜与开胸手术治疗肺隔离症疗效及安全性的文献。采用Review Manager 5.4软件对文献进行Meta分析。结果纳入17篇回顾性队列文献,共859例患者。Meta分析结果示:胸腔镜与开胸手术相比,手术时间短[MD=-14.09,95%CI(-27.82,-0.36),P<0.05]、出血量少[MD=-58.82,95%CI(-81.58,-36.05),P<0.01]、引流管留置时间短[MD=-1.67,95%CI(-2.39,-0.95),P<0.01]、住院时间降低[MD=-3.11,95%CI(-3.91,-2.31),P<0.01]。胸腔引流量差异无统计学意义[MD=-50.52,95%CI(-125.92,24.87),P=0.19]、并发症方面差异无统计学意义[OR=0.71,95%CI(0.41,1.22),P=0.21]。结论与开胸手术相比,胸腔镜手术时间、引流管留置时间、住院时间短、出血量更少,但两者在胸腔引流量和并发症方面效果相当。Objective To analyze and discuss the efficacy and safety of thoracoscopy and thoracotomy in the treatment of pulmonary sequestration.Methods Computer retrieval of KCI-Korean Journal Database,Pubmed,The Cochrane Library,EMbase,MEDLINE R,Wan Fang Date,Web of Science,CNKI database,and VIP database.From the establishment of the database to October 20,2022,the published literature on the efficacy and safety of thoracoscopy and thoracotomy in the treatment of pulmonary sequestration was searched.Meta analysis of literature was conducted using Review Manager 5.4 software.Results A total of 859 patients were included in 17 retrospective cohort studies.The meta-analysis results showed that compared with thoracotomy,thoracoscopy had shorter surgical time[MD=-14.09,95%CI(-27.82,-0.36),P<0.05],less bleeding[MD=-58.82,95%CI(-81.58,-36.05),P<0.01],shorter drainage tube retention time[MD=-1.67,95%CI(-2.39,-0.95),P<0.01],and reduced hospital stay[MD=-3.11,95%CI(-3.91,-2.31),P<0.01].There was no statistically significant difference in thoracic drainage flow rate[MD=-50.52,95%CI(-125.92,24.87),P=0.19],and there was no statistically significant difference in complications[OR=0.71,95%CI(0.41,1.22),P=0.21].Conclusion Compared with thoracotomy,thoracoscopic surgery has shorter time,drainage tube retention time,hospitalization time,and less bleeding,but both have similar effects in terms of thoracic drainage flow and complications.

关 键 词：肺隔离症 胸腔镜 开胸 系统评价/META分析 

分 类 号：R562.2[医药卫生—呼吸系统]