持续皮下注射与多次皮下注射胰岛素对1型糖尿病患儿的治疗效果分析  

Analysis of Therapeutic Effect of Continuous Subcutaneous Injection and Repeated Subcutaneous Injection of Insulin on Children with Type 1 Diabetes

作　　者：刘倩[1] Liu Qian(Guizhou Provincial People’s Hospital,Guiyang,Guizhou 550002)

机构地区：[1]贵州省人民医院,贵州贵阳550002

出　　处：《科技与健康》2023年第15期24-26,共3页Technology and Health

摘　　要：观察1型糖尿病患儿治疗中持续皮下注射胰岛素(CSII)与多次皮下注射胰岛素(MSII)应用效果。选取2016年12月—2022年12月贵州省人民医院收治的42例1型糖尿病患儿为研究对象,平均分为常规组(n=21,采用多次皮下注射胰岛素治疗)和持续组(n=21,采用持续皮下注射胰岛素治疗)。比较入院治疗5天后两组患儿TIR、TAR、TBR,观察治疗后两组患儿血糖达标时间、尿酮消失时间。结果显示,治疗后,持续组患儿TIR高于常规组,TAR、TBR低于常规组,且存在统计学差异(P<0.05);治疗后,持续组血糖达标时间、尿酮消失时间短于常规组,存在统计学差异(P<0.05)。研究发现,对1型糖尿病患儿采用持续皮下注射胰岛素治疗方式,血糖达标时间更长,血糖控制更为平稳,低血糖发生率低,可缩短血糖、尿酮等指标达标时间,值得临床广泛应用。To observe the effect of continuous subcutaneous insulin injection(CSII)and multiple subcutaneous insulin injection(MSII)in the treatment of children with type 1 diabetes.Forty two children with type 1 diabetes admitted to Guizhou Provincial People’s Hospital from December 2016 to December 2022 were selected as the study subjects,and were divided into the conventional group(n=21,treated with multiple subcutaneous injections of insulin)and the continuous group(n=21,treated with continuous subcutaneous injections of insulin).Compare the TIR,TAR,and TBR of two groups of children after 5 days of hospitalization treatment,and observe the time for blood glucose to reach the standard and the time for urine ketone to disappear in the two groups of children after treatment.The results showed that after treatment,the TIR of the continuous group was higher than that of the conventional group,while the TAR and TBR were lower than those of the conventional group,with statistical differences(P<0.05);After treatment,the duration of blood glucose reaching the standard and urine ketone disappearance time in the continuous group were shorter than those in the conventional group,with statistical differences(P<0.05).The study found that continuous subcutaneous injection of insulin treatment for children with type 1 diabetes can shorten the time for reaching the standard of blood sugar,control blood sugar more smoothly,and reduce the incidence of hypoglycemia,which is worth extensive clinical application.

关 键 词：持续皮下注射 多次皮下注射 胰岛素 糖尿病患儿 

分 类 号：R725.8[医药卫生—儿科]