可降解聚乙醇酸结晶行为与性能的构效关系  

Structure-Performance Relationship Between Crystallization Behavior and Properties of Degradable Polyglycolic acid

作　　者：田虎虎 韩德全 郭立影 王慧 齐钰璇 刘澜涛 曹鸿璋[1,3] TIAN Hu-hu;HAN De-quan;GUO Li-ying;WANG Hui;QI Yu-xuan;LIU Lan-tao;CAO Hong-zhang(Baotou Research Institute of Rare Earths,Baotou 014030,China;College of Chemistry and Chemical Engineering,Inner Mongolia University,Hohhot 010021,China;State Key Laboratory of Baiyunobo Rare Earth Resource Researches and Comprehensive Utilization,Baotou 014030,China)

机构地区：[1]包头稀土研究院,内蒙古包头014030 [2]内蒙古大学化学化工学院,内蒙古呼和浩特010021 [3]白云鄂博稀土资源研究与综合利用全国重点实验室,内蒙古包头014030

出　　处：《塑料科技》2023年第10期107-111,共5页Plastics Science and Technology

基　　金：中央引导地方科技发展资金项目(2022ZY0100);包头市“科技兴蒙”项目(XM2021CXZX02);内蒙古自治区人才开发基金项目(RS2201);包头市高端人才培育资助项目(RS2303);北方稀土项目(2022H_(2)377)。

摘　　要：聚乙醇酸(PGA)是半结晶聚酯材料,兼具生物降解性与生物相容性,在手术缝合线、组织支架等生物医用领域发挥重要作用。文章从PGA的化学结构、晶体结构、等温结晶动力学研究、非等温结晶动力学等方面详细论述PGA材料的高分子结晶热力学与动力学模型。研究表明:在加工工艺中对加工温度、压力和冷却速率等参数进行控制,可确保最终产品具有所需的性能。通过添加适当的添加剂或改变材料的分子结构可调节高分子材料的结晶度,以满足PGA在具体应用的使用要求,也为改善与拓展生物相容性PGA高分子材料的应用提供技术方案。Polyglycolic acid(PGA)is a semi-crystalline polyester material with biodegradability and biocompatibility.It plays an important role in biomedical fields such as surgical sutures and tissue scaffolds.The thermodynamic and kinetic models of polymer crystallization of PGA are discussed in detail from the aspects of chemical structure,crystal structure,isothermal crystallization kinetics and non-isothermal crystallization kinetics of PGA.The research shows that the parameters such as processing temperature,pressure and cooling rate can be controlled in the processing process to ensure that the final product has the required performance.By adding appropriate additives or changing the molecular structure of material,the crystallinity of the polymer material can be adjusted to meet the requirements of PGA in specific applications,and it also provides a technical solution for improving and expanding the application of biocompatible PGA polymer.

关 键 词：聚乙醇酸 非等温结晶 等温结晶 动力学模型 晶核 

分 类 号：TQ320.1[化学工程—合成树脂塑料工业]