中药白及在口腔疾病中的研究与应用  

Research and application of common bletilla rubber in oral diseases

作　　者：王湘滔 张爱娟 王万春 王芳萍 徐颖婕[1] 孟洋 Xiangtao Wang;Aijuan Zhang;Wanchun Wang;Fangping Wang;Yingjie Xu;Yang Meng(Qingdao Stomatological Hospital Affiliated to Qingdao University,Qingdao 266001,China)

机构地区：[1]青岛大学附属青岛市口腔医院,青岛266001

出　　处：《中华口腔医学研究杂志（电子版）》2023年第5期371-375,共5页Chinese Journal of Stomatological Research(Electronic Edition)

基　　金：青岛市医疗卫生重点学科建设项目(2022-2024);青岛市口腔疾病临床医学研究中心(22-3-7-1czx-7-nsh);青岛市医药卫生科研指导项目(2022-WJZD158)。

摘　　要：白及作为我国传统的中药材,分布广泛、价廉易得。随着中医药的蓬勃发展,白及在临床医学上的应用也更为深入,包括抗菌、抗肿瘤、治疗消化道溃疡、胃黏膜病变和体内外出血等。本文对白及的药理特性、化学成分做一总结,同时分析各成分在治疗中的机制和通路,着重归纳整理了白及在口腔疾病领域的应用,包括口腔黏膜类疾病、龋病、髓腔内屏障材料和牙周组织工程支架材料等,证明了白及无论是单味用药还是配伍用药,都能依靠其自身特性发挥重要功效,为进一步推广白及在口腔疾病治疗中的研究应用提供参考。As a traditional Chinese medicinal material,common bletilla rubber is widely distributed,cheap and easy to obtain.With the development of traditional Chinese medicine,common bletilla rubber is widely used in the treatment of bacterial infection,tumor,digestive tract ulcer,gastric mucosal lesions,external blood and so on.In this article,the pharmacological properties and chemical components of common bletilla rubber were summarized,and the mechanisms and pathways of each ingredient of common bletilla rubber were also analyzed.The application of common bletilla rubber in the field of oral diseases,including oral mucosal diseases,caries,intramedullary barrier materials and periodontal tissue engineering scaffold materials were summarized.It was proved that common bletilla rubber could play an important role in the fields above,no matter which form it was in.This article may provide reference for the further promotion of common bletilla rubber in the treatment of oral diseases.

关 键 词：白及 口腔疾病 口腔溃疡 龋病 髓腔穿孔 牙周组织工程 

分 类 号：R28[医药卫生—中药学]