超声造影成像检查对鉴别诊断甲状腺良恶性结节临床意义  

Clinical significance of contrast-enhanced ultrasound imaging in differential diagnosis of benign and malignant thyroid nodules

作　　者：徐姗姗 周彬 XU Shanshan;ZHOU Bin(Department of Ultrasound Medicine,Shangrao Municipal Hospital,Shangrao,Jiangxi,334000,China)

机构地区：[1]上饶市立医院超声医学科,江西上饶334000

出　　处：《当代医学》2023年第12期142-144,共3页Contemporary Medicine

摘　　要：目的探究超声造影成像检查对鉴别诊断甲状腺良恶性结节的临床意义。方法选取2020年3月至2021年3月本院收治的80例甲状腺结节患者作为研究对象,所有患者均实施超声造影成像检查,以手术病理结果为金标准,比较超声造影成像与手术病理的检查结果,观察超声造影成像检查诊断甲状腺结节的结果,并分析其诊断灵敏度、特异度及准确率。结果经手术病理学检查,阳性患者59例、阴性患者47例;以手术病理检查为“金标准”,超声造影成像检出阳性58例、阴性48例,其中检查误诊2例、漏诊3例,超声造影成像诊断甲状腺结节的灵敏度为94.92%、特异度为95.75%、准确率为95.28%,诊断价值较高。两个结节类型均匀增强占比比较差异无统计学意义;良性结节以环状高增强为主,占比87.50%,高于恶性结节的1.72%,差异有统计学意义(P<0.05);恶性结节以不均匀增强、低增强为主,占比为39.66%、53.45%,均高于良性结节的4.17%、2.08%,差异有统计学意义(P<0.05)。结论超声造影成像在甲状腺良恶性结节鉴别诊断中具有良好的应用价值,能显著提高甲状腺良恶性结节的诊断准确率,为患者治疗提供有效依据。Objective To explore the clinical significance of contrast-enhanced ultrasound imaging in the differential diagnosis of benign and malignant thyroid nodules.Methods A total of 80 patients with thyroid nodules admitted to our hospital from March 2020 to March 2021 were selected as the study subjects.All patients underwent contra-enhanced ultrasound imaging.The results of contra-enhanced ultrasound imaging were compared with those of surgical pathology,and the results of thyroid nodules diagnosed by contra-enhanced ultrasound imaging were observed.The diagnostic sensitivity,specificity and accuracy were analyzed.Results There were 59 positive patients and 47 negative patients by surgical pathology examination.With surgical pathologic examination as the"gold standard",58 positive cases and 48 negative cases were detected by CEUS,including 2 misdiagnosed cases and 3 missed cases.The sensitivity of contrast-enhanced ultrasound imaging in diagnosing thyroid nodules was 94.92%,the specificity was 95.75%,and the accuracy was 95.28%,diagnostic value is high.There was no significant difference in the proportion of uniform enhancement between the two nodules.The proportion of benign nodules with annular hyperenhancement was 87.50%,higher than 1.72%of malignant nodules,and the difference was statistically significant(P<0.05).Malignant nodules were mainly characterized by uneven enhancement and low enhancement,accounting for 39.66%and 53.45%,which were higher than 4.17%and 2.08%of benign nodules,and the differences were statistically significant(P<0.05).Conclusion Contrast-enhanced ultrasound imaging has good application value in the differential diagnosis of benign and malignant thyroid nodules,can significantly improve the diagnostic accuracy of benign and malignant thyroid nodules,and provide effective basis for the treatment of patients.

关 键 词：甲状腺结节 良恶性 超声造影成像 

分 类 号：R445.1[医药卫生—影像医学与核医学] R736.1[医药卫生—诊断学]