2016—2021年单中心161例早中期非哺乳期乳腺炎治疗方式回顾性分析  

Retrospective analysis of treatment modalities for 161 cases of early to mid-stage nonlactating mastitis in a single center in 2016—2021

作　　者：乔伟强 邓淼[1] 刘起鹏[1] 高宇 候成彬 郭婉莹 陈登庭[1] QIAO Weiqiang;DENG Miao;LIU Qipeng;GAO Yu;HOU Chengbin;GUO Wanying;CHEN Dengting(Department of Breast Surgery,The First Affiliated Hospital,and College of Clinical Medicine of Henan University of Science and Technology,Luoyang,Henan 471000,China;Department of Thyroid and Breast Surgery,Luoyang 5111 Hospital,Luoyang,Henan 471000,China)

机构地区：[1]河南科技大学第一附属医院乳腺外科,河南洛阳471000 [2]洛阳5111医院甲状腺乳腺外科,河南洛阳471000

出　　处：《安徽医药》2023年第12期2483-2486,共4页Anhui Medical and Pharmaceutical Journal

摘　　要：目的探讨早中期非哺乳期乳腺炎病人的不同临床治疗方式的治疗效果。方法回顾性分析2016年11月至2021年10月于河南科技大学第一附属医院乳腺外科就诊的161例早中期非哺乳期乳腺炎病人的临床资料。该院早中期非哺乳期乳腺炎的治疗方式主要有中药内服+手术治疗和抗生素联合类固醇激素疗法+手术治疗。病人分为两组,中药内服+手术治疗组(n=79),抗生素联合类固醇激素疗法+手术治疗组(n=82)。运用χ2检验对病人的临床病历资料特征进行分析,运用t检验对病人的临床疗效、疼痛消失时间、红肿消失时间、肿块消失时间和治疗时间进行分析。结果抗生素联合类固醇激素疗法+手术治疗组的疼痛消失时间(6.76±1.25)d、红肿消失时间(7.51±1.33)d和中药内服+手术治疗组的疼痛消失时间(7.48±1.83)d、红肿消失时间(8.23±1.93)d相比,差异有统计学意义(P<0.05);两组均达到较高的临床总有效率[91.14%(72/79)比87.80%(72/82),P=0.515],两组在肿块消失时间及治疗时间方面比较差异无统计学意义(P>0.05)。结论该院早中期非哺乳期乳腺炎病人的不同临床治疗方式中,两组均达到较高的临床总有效率,抗生素联合类固醇激素疗法+手术治疗可以更加快速缩短疼痛消失时间及红肿消失时间,两种治疗方式在肿块消失时间及治疗时间方面比较差异无统计学意义。Objective To explore the therapeutic effect of different clinical treatment modalities in patients with early-to mid-stage nonpuerperal mastitis(NPM).Methods The clinical data of 161 patients with early-to mid-stage NPM who attended the Department of Breast Surgery at the First Affiliated Hospital of Henan University of Science and Technology from November 2016 to October 2021 were retrospectively analyzed.The main treatment modalities of early to mid-stage NPM patients in this center were internal traditional Chinese medicine+surgery treatment and antibiotics combined with steroid hormone therapy+surgery treatment.The patients were divided into two groups:the traditional Chinese medicine+surgical treatment group(n=79)and the antibiotic combined with steroid hormone therapy+surgical treatment group(n=82).The characteristics of the patients'clinical history data were analyzed using the chisquare test,and the clinical efficacy,time to disappearance of pain,time to disappearance of redness and swelling,time to disappearance of lumps,and time to treatment were analyzed using the t test.Results The pain disappearance time(6.76±1.25)d and redness disappearance time(7.51±1.33)d in the antibiotics combined with steroid hormone therapy+surgery treatment group,were statistically significant compared with the pain disappearance time(7.48±1.83)d and redness disappearance time(8.23±1.93)d in the traditional Chinese medicine intranasal medicine+surgery treatment group(P<0.05).Both groups achieved a high total clinical effectiveness rate[91.14%(72/79)than 87.80%(72/82),P=0.515]and the difference between the two groups in terms of the time of disappearance of lumps and the time of treatment was not statistically significant when compared with each other(P>0.05).Conclusions Both groups achieved a high total clinical effectiveness rate in different clinical treatment modalities for early and mid-stage NPM patients in this center.Antibiotics combined with steroid hormone therapy+surgical treatment can shorten the time of pain d

关 键 词：乳腺炎 早期医疗干预 奥硝唑 甲泼尼龙 引流术 非哺乳期 中药 

分 类 号：R655.8[医药卫生—外科学]