饮用水中抗生素抗性基因分布及暴露风险研究进展  

DISTRIBUTION OF ANTIBIOTIC RESISTANCE GENES AND EXPOSURE RISK IN DRINKING WATER:A REVIEW

作　　者：曾光曙 周振超 林彦含 葛子冶 林泽俊 帅馨怡 周津羽 陈红[1] ZENG Guangshu;ZHOU Zhenchao;LIN Yanhan;GE Ziye;LIN Zejun;SHUAI Xinyi;ZHOU Jinyu;CHEN Hong(Research Institute of Evironmental Technology,College of Environmental and Resource Sciences,Zhejiang University,Hangzhou 310058,China)

机构地区：[1]浙江大学环境与资源学院环境技术研究所,杭州310058

出　　处：《环境工程》2023年第9期114-123,共10页Environmental Engineering

基　　金：中央高校基本科研业务费专项资金(226-2023-00117);国家自然科学基金项目(52270201)。

摘　　要：抗生素耐药性的传播已成为全球性的公共健康问题,饮用水作为抗生素抗性基因(antibiotics resistance genes,ARGs)向人体迁移传播的重要途径,其携带的抗性基因及潜在暴露风险引起了广泛关注。基于已发表的饮用水ARGs相关研究,分析了全球范围饮用水中ARGs的分布及其影响因素,探究了适用于表征饮用水中ARGs人群暴露剂量及暴露风险的评估方法,并探讨了当前常规饮用水处理技术在控制ARGs方面的作用及局限性。未来的研究可从传播性、人类致病性等多维度对饮用水抗生素耐药风险进行系统性评估,针对ARGs去除需开发新型水处理技术对其进行强化处理。The spread of antibiotic resistance has become a global public health issue.Drinking water is an important pathway for the migration and dissemination of antibiotic resistance genes(ARGs)to the human body.The ARGs and their potential exposure risks in drinking water have attracted widespread attention.This review summarized the distribution of ARGs in drinking water worldwide and its drivers based on published research on ARGs in drinking water.It explored the assessment methods applicable to characterize the exposure dose and risk of ARGs in drinking water,and discussed the effects and limitations of conventional drinking water treatment technologies in controlling ARGs.Further studies were required to conduct systematic assessments of antibiotic resistance risks in drinking water from multiple dimensions(e.g.transmissibility and human pathogenicity)and develop novel water treatment technologies to enhance the removal of ARGs.

关 键 词：饮用水 抗生素抗性基因 丰度分布 暴露风险 处理技术 

分 类 号：TU991.21[建筑科学—市政工程] X52[环境科学与工程—环境工程]