无糖配方全肠外营养液相关不良事件病例分析及调整策略探讨  

Analysis of adverse events in total parenteral nutrition solution with sugar-free formula and discussion on adjustment strategy

作　　者：聂婧栩[1] 崔凯霞 祁雪妍 郝志英[1] 陈莲珍 NIE Jing-xu;CUI Kai-xia;QI Xue-yan;HAO Zhi-ying;CHEN Lian-zhen(Department of Pharmacy,Shanxi Province Cancer Hospital,Shanxi Hospital Affiliated to Cancer Hospital,Chinese Academy of Medical Sciences,Cancer Hospital Affiliated to Shanxi Medical University,Taiyuan 030000,China;School of Pharmaceutical Sciences,Shanxi Medical University,Taiyuan 030001,China;Department of Pharmacy,National Cancer Center,National Clinical Research Center for Cancer,Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,China)

机构地区：[1]山西省肿瘤医院/中国医学科学院肿瘤医院山西医院/山西医科大学附属肿瘤医院药学部,太原030000 [2]山西医科大学药学院,太原030001 [3]国家癌症中心/国家肿瘤临床医学中心/中国医学科学院北京协和医学院肿瘤医院药剂科,北京100021

出　　处：《临床药物治疗杂志》2023年第10期87-89,共3页Clinical Medication Journal

基　　金：国家重点研发计划项目(2016YFA0201504);山西省重点研发计划(指南)项目(201603D321105)。

摘　　要：本文报道了患者使用无糖配方全肠外营养液后出现代谢并发症,通过添加葡萄糖注射液供能,减少脂肪供能后并发症消失的临床不良事件案例,并探讨分析其原因和应采取的调整策略。肠外营养强调葡萄糖和脂肪乳双能源供能,在临床应用中应重视肠外营养液配方中糖脂比的合理性,糖脂比合理范围应控制在50~70∶30~50。This paper reports the cases of metabolic complications after patients used sugar-free total parenteral nutrition solution.By adding glucose and reducing fat emulsion for energy supply,the adverse event diminished.The causes of the ad⁃verse event and adjustment strategies are discussed and analyzed.Parenteral nutrition emphasizes the dual energy supply of glucose and fat emulsion.In clinical practice,attention should be paid to the rationality of the glucose-fat ratio in the formula of parenteral nutrition.The reasonable range of the glucose-fat ratio should be controlled at 50-70∶30-50.

关 键 词：全肠外营养 无糖配方 糖脂比 合理使用 

分 类 号：R977.9[医药卫生—药品] R969.3[医药卫生—药学]