小儿热速清糖浆联合对乙酰氨基酚治疗持续高热小儿表里俱热证的效果  

Effect of Pediatric Resuqing Syrup combined with Acetaminophen in the Treatment of Chronic Hyperthermia Syndrome in Children

作　　者：岳云超 闫严 YUE Yun-Chao;YAN Yan(Department of Emergency,Baoding Hospital,Beijing Children's Hospital Affiliated to Capital Medical University,Beijing 071000,China)

机构地区：[1]首都医科大学附属北京儿童医院保定医院急诊科,河北保定071000

出　　处：《中国药物经济学》2023年第9期87-90,共4页China Journal of Pharmaceutical Economics

摘　　要：目的探讨小儿热速清糖浆联合对乙酰氨基酚治疗持续高热小儿表里俱热证的效果。方法选取2021年2月至2022年8月首都医科大学附属北京儿童医院保定医院儿科收治的持续高热小儿表里俱热证患儿120例作为研究对象,按照随机数字表法分为对照组和观察组,各60例。对照组采用对乙酰氨基酚治疗,观察组在对照组基础上联合小儿热速清糖浆治疗。比较两组治疗效果、完全退热时间、退热无反复率、症状积分变化以及血清炎症因子变化情况。结果观察组治疗有效率为95.00%,高于对照组的81.67%,不良反应发生率5.00%低于对照组的16.67%,完全退热时间短于对照组,退热无反复率96.37%,高于对照组的68.33%,差异有统计学意义(P<0.05);治疗后观察组症状评分低于对照组,超敏C反应蛋白(hs-CRP)、白细胞介素-6(IL-6)、降钙素原(PCT)水平低于对照组,差异有统计学意义(P<0.05)。结论小儿热速清糖浆联合对乙酰氨基酚治疗持续高热小儿表里俱热证效果明确,可尽快缓解患儿相关症状,缩短退热时间,且退热无反复,起到疏风散热的效果,具有较高的应用价值。Objective To explore the effect of pediatric Resuqing syrup combined with acetaminophen in the treatment of chronic hyperthermia syndrome in children.Methods From February 2021 to August 2022,120 children with persistent hyperthermia syndrome in the Department of Pediatrics,Baoding Hospital,Beijing Children's Hospital Affiliated to Capital Medical University were selected as the study objects,and were divided into control group and observation group according to random number table method,with 60 cases each.The control group was treated with acetaminophen,and the observation group was treated with pediatric Resuqing syrup on the basis of control group.The therapeutic effect,the time of complete remission of fever,the rate of no recurrence of fever,the change of symptom score and the change of serum inflammatory factors were compared between the two groups.Results The effective rate of the observation group was 95.00%,higher than that of the control group(81.67%),the incidence of adverse reactions was 5.00%,lower than that of the control group(16.67%),the time of complete fever regression was shorter than that of the control group,the rate of fever regression without recurrence was 96.37%,higher than that of the control group(68.33%),with statistical significance(P<0.05).After treatment,the symptom score of observation group was lower than that of control group,and the levels of hypersensitive C-reactive protein(hs-CRP),interleukin-6(IL-6)and procalcitonin(PCT)were lower than those of control group,with statistical significance(P<0.05).Conclusion Children's Resuqing syrup combined with acetaminophen in the treatment of persistent hyperthermia in children has a clear effect,can alleviate the related symptoms of children as soon as possible,shorten the time of fever,and fever without repetition,play a dissipating wind heat dissipation effect,with high application value.

关 键 词：小儿热速清糖浆 对乙酰氨基酚 持续高热 表里俱热证 中西医结合疗法 

分 类 号：R725.6[医药卫生—儿科] R985[医药卫生—临床医学]