机构地区:[1]南通大学第二附属医院心超室,江苏南通226000 [2]南通大学第二附属医院心血管内科,江苏南通226000
出 处:《现代生物医学进展》2023年第18期3564-3567,3581,共5页Progress in Modern Biomedicine
基 金:江苏省卫健委老年健康科研项目(LKM2022060)。
摘 要:目的:探讨与分析超声三维斑点技术联合SYNTAX评分对冠心病病情的判断价值。方法:2022年2月到2023年1月选择在医院诊治的冠心病患者350例作为研究对象,所有患者都给予超声三维斑点检查,同时所有患者都给予SYNTAX评分。随访记录患者的主要不良心血管事件(MACE)发生情况病进行相关性分析。结果:在350例患者中,随访到2023年2月1日,平均随访时间为9.14±1.13个月,发生MACE45例(MACE组),占比12.9%,其中心源性死亡6例、冠脉综合征14例、血运重建13例、恶性心律失常7例、心力衰竭5例。MACE组的年龄、体重指数、性别、总胆固醇(TG)、高密度脂蛋白(HDL-C)、低密度脂蛋白(LDL-C)、甘油三酯(TC)血糖与非MACE组对比无显著差异(P>0.05)。MACE组的超声三维斑点参数-右室收缩峰值应变率(SRs)高于非MACE组(P<0.05),右室舒张晚期峰值应变率(SRa)、舒张早期峰值应变率(SRc)与非MACE组对比有显著降低(P<0.05)。MACE组的SYNTAX评分明显高于非MACE组(P<0.05),两组的SYNTAX评分分级人群占比也有显著差异(P<0.05)。在350例患者中,Spearsman分析显示SYNTAX评分、SRs、SRc、SRa都与MACE的发生呈现正相关性(P<0.05)。logistic回归分析法显示SYNTAX评分、SRs、SRc、SRa都为导致MACE发生的重要因素(P<0.05)。结论:冠心病患者治疗后MACE的发生率依然比较高,多伴随有SYNTAX评分增高,超声三维斑点技术检查也存在一定的差异性,超声三维斑点技术联合SYNTAX评分能有效反映冠心病患者的病情。Objective:To explore and analysis the values of three-dimensional ultrasound speckle technique combined with SYNTAX score in the diagnosis of coronary heart disease.Methods:From February 2022 to January 2023,350 cases of patients with coronary heart disease diagnosed and treated in a certain hospital were selected as the study subjects.All patients were given three-dimensional ultrasound spot examination,and all patients were given SYNTAX score.The incidence of major adverse cardiovascular event(MACE)of the patients were followed up and recorded for correlation analysis.Results:In the 350 patients,the average follow-up time were 9.14±1.13 months until February 1,2023.There were 45 cases of MACE(MACE group),accounting for 12.9%,included 6 cases of cardiac death,14 cases of coronary syndrome,13 cases of revascularization,7 cases of malignant arrhythmia,and 5 cases of heart failure.There were no significant difference in age,body mass index,sex,total cholesterol(TG),high-density lipoprotein(HDL-C),low density lipoprotein(LDL-C),triglyceride(TC)blood glucose compared between MACE group and non-MACE group(P>0.05).The three-dimensional ultrasound speckle parameter-right ventricular systolic peak strain rate(SRs)in the MACE group were higher than that in the non-MACE group(P<0.05),and the right ventricular late diastolic peak strain rate(SRa)and early diastolic peak strain rate(SRc)were significantly lower than those in the non-MACE group(P<0.05).The SYNTAX scores of the MACE group were significantly higher than that of the non-MACE group(P<0.05),and there were also significant difference in the proportion of people in the SYNTAX score grading compared between the two groups(P<0.05).In the 350 patients,Spearman analysis showed that SYNTAX score,SRs,SRc and SRa were positively correlated with the occurrence of MACE(P<0.05).Logistic regression analysis showed that SYNTAX score,SRs,SRc and SRa were important factors leaded to MACE(P<0.05).Conclusion:The incidence of MACE in patients with coronary heart disease after treat
分 类 号:R541.4[医药卫生—心血管疾病]
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