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作 者:Laura Torrejón-Rodríguez Álvaro Solaz-García Inmaculada Lara-Cantón Alejandro Pinilla-González Marta Aguar Máximo Vento
机构地区:[1]Division of Neonatology,University and Polytechnic Hospital La Fe(HULAFE),Valencia 46026,Spain [2]Neonatal Research Group,Instituto de Investigación Sanitaria La Fe(IISLAFE),Valencia 46026,Spain
出 处:《Maternal-Fetal Medicine》2023年第4期244-247,共4页母胎医学杂志(英文)
基 金:L.T.-R.enjoys a“Post-MIR”predoctoral research grant from the Health Research Institute La Fe(IISLAFE).I.L.-C.and A.P.-G.enjoy Rio Hortega predoctoral grants from the Instituto de Investigación en Salud Carlos III(Ministry of Science,Spain).
摘 要:Extreme preterm infants(<28 weeks'gestation)often require positive pressure ventilation with oxygen during postnatal stabilization in the delivery room.To date,optimal inspired fraction of oxygen(FiO_(2))still represents a conundrum in newborn care oscillating between higher(>60%)and lower(<30%)initial FiO_(2).Recent evidence and meta-analyses have underscored the predictive value for survival and/or relevant clinical outcomes of the Apgar score and the achievement of arterial oxygen saturation measured by pulse oximetry≥85%at 5 minutes after birth.New clinical trials comparing higher versus lower initial FiO_(2)have been launched aiming to optimize postnatal stabilization of extreme preterm while avoiding adverse effects of hypoxemia or hyperoxemia.
关 键 词:Extreme preterm Postnatal stabilization Oxygen saturation Heart rate Inspired fraction of oxygen Apgar score
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