2013—2022年深圳市登革热流行特征分析  

Analysis on the epidemiological characteristics of dengue fever in Shenzhen from 2013 to 2022

作　　者：万佳 林良强[1] 阳帆[1] 李媛[1] 牛丛 高世同[1] 张振[1] 孔东锋[1] WAN Jia;LIN Liangqiang;YANG Fan;LI Yuan;NIU Cong;GAO Shitong;ZHANG Zhen;KONG Dongfeng(Shenzhen Center for Disease Control and Prevention,Shenzhen 518055,Guangdong Province,China)

机构地区：[1]深圳市疾病预防控制中心,广东深圳518055

出　　处：《热带病与寄生虫学》2023年第5期258-262,共5页Journal of Tropical Diseases and Parasitology

基　　金：深圳市医学重点学科(公共卫生重点专科)项目(SZXK064);深圳市“医疗卫生三名工程”项目(SZSM202011008)。

摘　　要：目的对深圳市登革热流行特征进行分析,为登革热防控工作提供参考。方法通过中国疾病预防控制信息系统收集2013—2022年深圳市登革热病例资料,采用描述流行病学方法对病例三间分布特征、病例感染地、发病至确诊时间、疫情暴发情况以及病原和蚊媒监测结果进行分析。结果2013—2022年深圳市累计报告登革热病例1388例,各年度发病率0~4.75/10万。其中本地病例650例,境外输入病例533例,境内输入病例205例。报告病例较多的年份为2014年(454例)和2019年(523例),病例主要集中在8—11月(1112例,占80.12%)。深圳市10个行政区均有病例发生,涉及范围占全市街道总数的90.54%。病例年龄中位数为34(27,45)岁,20~59岁1238例(占89.19%);男女比例1.80:1;职业分布前3位为工人、家务及待业和商业服务(共958例,占69.02%)。境外输入病例主要来自东南亚国家(528例,占99.06%),境内输入病例主要来自珠三角地区(151例,占73.66%)。病例从发病到确诊间隔时间中位数为5(3,7)d。本地暴发疫情20起,主要发生在建筑工地(10起),10月发生最多(9起)。存在多种血清型流行,以DENV-1型为主,占83.31%(594/713)。健康人群血清登革病毒IgG抗体阳性率为1.98%,各年度阳性率差异无统计学意义(χ^(2)=3.01,P>0.05)。每年5—11月为白纹伊蚊活跃期。结论深圳市登革热流行态势较为严峻,病例数较前十年上升,本地病例主要由输入病例引起,需加强对输入病例的监测和疫情处置工作。Objective To analyze the epidemiological characteristics of dengue fever in Shenzhen area from 2013 to 2022 for evidences in prevention and control of this infection.Methods The data of dengue cases reported in Shenzhen area from 2013 to 2022 were retrieved from the China Disease Prevention and Control Information System.Descriptive epidemiology was used to analyze the characteristics of spatial,time and population distribution,infection places,the time from disease onset to definite diagnosis,outbreak status,and results of pathogen and mosquito vector monitoring.Results From 2013 to 2022,1388 dengue cases were reported in Shenzhen,the annual incidence was 4.45/100000.Among them,there are 650 local cases,533 foreign imported cases,and 205 imported cases domestically.The most reported cases were in 2014(454 cases)and 2019(523 cases),and the most reported months were from August to November(1112 cases,80.12%).The infection occurred in 10 administrative districts,accounting for 90.54%of the total community regions in the city.The median age at disease onset was 34(27,45)years,and the epidemic mainly occurred in population aged 20-59 years(1238 cases,89.19%).Male to female ratio was 1.80:1.The top three occupation was workers,housework and unemployed,business services(958 cases,69.02%).The foreign imported cases were primarily from southeast Asian countries(528 cases,99.06%),while the domestic imported cases were generally from Pearl River Delta areas(151 cases,73.66%).The median interval from onset to diagnosis was 5(3,7)days.Twenty local outbreaks were reported,ten outbreaks occurred in local construction sites,and 9 events occurred in October.Although multiple serotypes were prevalent,yet DENV-1 was predominant in both imported and local infections(83.31%,597/713).The positive rate of serum dengue virus IgG antibody in healthy individuals was 1.98%,and there was no statistically significant difference in the positive rates among different years(χ^(2)=3.01,P>0.05).The active period of Aedes albopictus was from May

关 键 词：登革热 流行特征 血清型 白纹伊蚊 深圳市 

分 类 号：R373.33[医药卫生—病原生物学]