母乳对生命早期T细胞免疫功能影响的研究  

Research progress in the effects of breast milk on T cell immune function in early life

作　　者：朱思敏 张雯婷 屠文娟[3] ZHU Simin;ZHANG Wenting;TU Wenjuan(Graduate School,Medical School of Nantong University,Nantong,Jiangsu 226000,China;Pediatric Centeral Laboratory,Affliated Changzhou Children's Hospital of Nantong University,Nantong,Jiangsu 226000,China;Center for Children's Health Promotion,Affiliated Changzhou Children's Hospital of Nantong University,Nantong,Jiangsu 226000,China)

机构地区：[1]南通大学医学院研究生院,江苏南通226000 [2]南通大学附属常州儿童医院儿科中心实验室,江苏南通226000 [3]南通大学附属常州儿童医院儿童健康促进中心,江苏南通226000

出　　处：《中国儿童保健杂志》2023年第8期868-872,共5页Chinese Journal of Child Health Care

基　　金：国家自然科学基金(81801493)。

摘　　要：不同于成人的免疫系统,婴儿的免疫系统尚未发育成熟。母乳是生命早期免疫功能趋向成熟的关键条件,因为母乳中的生物活性成分能够直接影响并且可以通过促进肠道菌群的定植间接影响T细胞免疫功能,从而减少病原体的感染及过度炎症对机体的损害。本篇综述主要总结了母乳对生命早期T细胞免疫功能的影响,旨在加强人们对母乳重要性的认识,促进母乳喂养。Different from adult,the immune systems of infants are not yet mature.Breast milk is a key condition for the maturation of immune function early in life,because that bioactive components in breast milk can not only directly promote the development of T cell immune function but also affect it indirectly by promoting the colonization of intestinal flora.As a result,the infection of pathogens and excessive inflammation damage to the body would be reduced.This review mainly summarizes the effects of breast milk on T cell immune function in early life,aiming to raise awareness of the importance of breast milk and to promote breastfeeding.

关 键 词：母乳 T细胞 免疫 肠道菌群 人乳低聚糖 

分 类 号：R392[医药卫生—免疫学]