穴位贴敷治疗阻塞性睡眠呼吸暂停低通气综合征的疗效观察  

Efficacy observation of acupoint application in treating obstructive sleep apnea-hypopnea syndrome

作　　者：李汉 鲁明霞 胡照 LI Han;LU Mingxia;HU Zhao(Zhejiang Chinese Medical University,Hangzhou 311403,China;Zhejiang Jinhua People’s Hospital,Jinhua 321000,China;Zhejiang Jinhua Hospital of Chinese Medicine,Jinhua 321000,China)

机构地区：[1]浙江中医药大学,杭州311403 [2]浙江省金华市人民医院,金华321000 [3]浙江省金华市中医医院,金华321000

出　　处：《上海针灸杂志》2023年第11期1140-1144,共5页Shanghai Journal of Acupuncture and Moxibustion

摘　　要：目的观察穴位贴敷治疗阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea-hypopnea syndrome,OSAHS)的临床疗效。方法将80例OSAHS患者随机分为治疗组和对照组,每组40例。在常规治疗的基础上,治疗组给予中药药粉制成的药饼贴于穴位,对照组给予安慰剂制成的药饼贴于穴位。观察两组治疗前后呼吸暂停低通气指数(apnea-hypopnea index,AHI)、最低氧饱和度(arterial oxygen saturation,SaO2)、觉醒指数(arousal index,ArI)及Epworth嗜睡量表(Epworth sleepiness scale,ESS)评分变化,并比较两组临床疗效。结果治疗组总有效率为67.5%,对照组总有效率为37.5%,两组比较差异有统计学意义(P<0.01)。治疗后,两组AHI均降低,且治疗组低于对照组,差异有统计学意义(P<0.01)。治疗后,两组最低SaO2均升高,且治疗组高于对照组,差异有统计学意义(P<0.01)。治疗后,两组ArI均降低(P<0.01),且治疗组低于对照组(P<0.05)。治疗后,两组ESS评分均降低(P<0.01),组间比较差异无统计学意义(P>0.05)。结论在常规治疗基础上,穴位贴敷治疗能降低OSAHS患者AHI,减少睡眠呼吸事件,改善低氧血症,减少夜间觉醒次数,一定程度上恢复睡眠完整性。Objective To observe the clinical efficacy of acupoint application in treating obstructive sleep apnea-hypopnea syndrome(OSAHS).Method Eighty patients with OSAHS were randomized into a treatment group and a control group,with 40 cases in each group.Aside from the conventional treatment,medicinal cakes made of Chinese medicine powder were applied to acupoints in the treatment group,and medicinal cakes made of placebo were applied to acupoints in the control group.Before and after the treatment,the apnea-hypopnea index(AHI),the lowest arterial oxygen saturation(SaO2),arousal index(ArI),and Epworth sleepiness scale(ESS)score were observed,and the clinical efficacy was compared between the two groups.Result The total effective rate was 67.5%in the treatment group versus 37.5%in the control group;the between-group difference was statistically significant(P<0.01).After the treatment,the AHI dropped in both groups and was lower in the treatment group than in the control group,presenting statistical significance(P<0.01).The lowest SaO2 increased after the treatment in the two groups and was significantly higher in the treatment group than in the control group(P<0.01).After the treatment,the ArI decreased in both groups(P<0.01)and was lower in the treatment group than in the control group(P<0.05).The ESS score declined after the treatment in both groups(P<0.01),but the between-group difference was statistically insignificant(P>0.05).Conclusion Based on the conventional treatment,acupoint application can lower AHI,reduce sleep-related breathing events,improve hypoxemia,and reduce nocturnal arousal frequency in OSAHS patients,restoring sleep integrity to some extent.

关 键 词：睡眠呼吸暂停 阻塞性 穴位贴敷法 呼吸暂停低通气指数 EPWORTH嗜睡量表 觉醒指数 

分 类 号：R246.1[医药卫生—针灸推拿学]