Engineered microneedles arrays for wound healing  

作　　者：Shun Yao Yuan Luo Yongan Wang 

机构地区：[1]State Key Laboratory of Toxicology and Medical Countermeasures,Beijing Institute of Pharmacology and Toxicology,Beijing 100850,China

出　　处：《Engineered Regeneration》2022年第3期232-240,共9页再生工程（英文）

基　　金：supported by the Special Fund for Military Medical Science(AWS17J009).

摘　　要：Wound healing is the regenerative process of original skin structure after destructing by different damage sources.Due to their transdermal delivery capability and high specific surface area,microneedles arrays(MAs)have been recognized as encouraging biomaterials for wound healing.In this review,we have outlined the engineered MAs used for tissue regeneration and wound healing.Engineered MAs were first classified by design methodologies such as bionic design,intelligent-responsive design,actively-triggered design,matrix materials innovation,and composite smart design.Then,the MAs were divided into two categories based on the different loading substances:drug-loaded MAs and living component-loaded MAs.Finally,we have summed up the important elements of the preceding discussions and forecasted their future evolution.

关 键 词：Engineered design Microneedles arrays Wound healing 

分 类 号：TH77[机械工程—仪器科学与技术]