膈下逐瘀汤加减联合针刺治疗气滞血瘀证盆腔炎后遗症的疗效及对炎症指标、血液流变学的影响  

Efficacy of Modified Diaphragmatic Stasis Expelling Decoction Combined with Acupuncture on Sequelae of Pelvic Inflammatory Disease with Qi Stagnation and Blood Stasis Syndrome and Its Effects on Inflammatory Indicators and Hemorheology

作　　者：程晓嫚 田丽颖[1] 王芬 成自霞 CHENG Xiaoman;TIAN Liying;WANG Fen;CHENG Zixia(Dept.of Gynaecology,the Second Affiliated Hospital of Anhui University of Traditional Chinese Medicine,Hefei 230000,China)

机构地区：[1]安徽中医药大学第二附属医院妇科,合肥230000

出　　处：《中国医院用药评价与分析》2023年第9期1056-1059,共4页Evaluation and Analysis of Drug-use in Hospitals of China

基　　金：田丽颖全国名老中医药专家传承工作室项目[No.国中医药人教函[2022]75号];安徽省“十三五”省级重点中医专科建设项目[No.卫办秘[2016]680号]。

摘　　要：目的:观察膈下逐瘀汤加减联合针刺治疗盆腔炎后遗症(SPID)的疗效及对炎症指标、血液流变学的影响。方法:选取2018年7月至2022年7月该院收治的气滞血瘀证SPID患者60例,按就诊顺序编号,以随机数字表法分为对照组、观察组,每组30例。对照组患者给予注射用头孢西丁钠联合乳酸左氧氟沙星注射液静脉滴注;观察组患者在对照组的基础上给予膈下逐瘀汤加减联合针刺治疗。两组患者每个月经周期连续治疗10 d,共治疗3个月经周期。治疗前后测定两组患者的超敏C反应蛋白(hs-CRP)、白细胞计数(WBC)、中性粒细胞百分比(NEUT%)、纤维蛋白原(FIB)和血细胞比容(HCT),将证候、体征进行量化评分,观察两组患者症状缓解时间,评估疗效,并比较两组患者的总满意度。结果:治疗后,观察组患者的hs-CRP、WBC、NEUT%、FIB和HCT水平均较对照组明显降低,差异均有统计学意义(P<0.05)。观察组患者的证候、体征评分均较对照组降低明显,症状缓解时间较对照组明显缩短,差异均有统计学意义(P<0.05)。观察组患者的总有效率、总满意度分别为93.33%(28/30)、90.00%(27/30),明显高于对照组的80.00%(24/30)、76.67%(23/30),差异均有统计学意义(P<0.05)。结论:在静脉滴注抗菌药物的基础上给予膈下逐瘀汤加减联合针刺治疗气滞血瘀证SPID,可调节患者炎症指标和血液流变学,改善症状,提高疗效,患者满意度高。OBJECTIVE:To observe the efficacy of modified diaphragmatic stasis expelling decoction combined with acupuncture on sequelae of pelvic inflammatory disease(SPID) with Qi stagnation and blood stasis syndrome and its effects on inflammatory indicators and hemorheology.METHODS:A total of 60 patients with SPID of Qi stagnation and blood stasis admitted into the hospital from Jul.2018 to Jul.2022 were extracted to be divided into the control group and observation group according to the admission sequence with random number table method,with 30 cases in each group.The control group was treated with cefoxitin sodium and levofloxacin lactate injection by intravenous drip,on this basis,the observation group was given modified diaphragmatic stasis expelling decoction combined with acupuncture.Two groups were treated for 10 d per menstrual cycle,with a total of 3 menstrual cycles.The levels of high-sensitivity c-reactive protein(hs-CRP),white blood cell(WBC),neutrophil percentage(NEUT%),fibrinogen(FIB) and hematocrit(HCT) before and after treatment were detected in both groups.The syndromes and signs were quantitatively scored.The relief time of symptom was observed,the curative effect was evaluated,and the total satisfaction degree was compared between two groups.RESULTS:After treatment,the levels of hs-CRP,WBC,NEUT%,FIB,HCT in the observation group were significantly lower than those in control group,with statistically significant difference(P<0.05).The scores of symptoms and signs in the observation group were significantly lower than those in control group,and the relief time of symptoms was significantly shorter than that in control group,with statistically significant differences(P<0.05).The total effective rate and satisfaction degree of the observation group were respectively 93.33%(28/30) and 90.00%(27/30),significantly higher than 80.00%(24/30) and 76.67%(23/30) of control group,with statistically significant difference(P<0.05).CONCLUSIONS:On the basis of intravenous drip of antibiotics,modified diaphragmatic stas

关 键 词：盆腔炎后遗症 气滞血瘀证 膈下逐瘀汤加减 针刺 炎症指标 血液流变学 

分 类 号：R932[医药卫生—生药学]