心血管疾病合并肌少症的影响因素研究  

Factors affecting concurrent sarcopenia among patients with cardiovascular diseases

作　　者：马润泽 石芳[2] 李洪全[2] 吕梦竹 努尔比亚木·艾合提 田小丽 陈思敏 晏师康 开地日艳·库日班江 杨蕾[1,4] MA Runze;SHI Fang;LI Hongquan;LÜMengzhu;Nuerbiyamu Aiheti;TIAN Xiaoli;CHEN Simin;YAN Shikang;Kaidiriyan Kuribanjiang;YANG Lei(School of Public Health,Xinjiang Medical University,Urumqi,Xinjiang 830054,China;The Sixth Division Hospital of Xinjiang Production and Construction Corps,Wujiaqu,Xinjiang 831300,China;Xinjiang Second Medical College,Karamay,Xinjiang 834000,China;State Key Laboratory of Causes and Prevention of High Incidence in Central Asia,Urumqi,Xinjiang 830011,China)

机构地区：[1]新疆医科大学公共卫生学院,新疆乌鲁木齐830054 [2]新疆生产建设兵团第六师医院,新疆五家渠831300 [3]新疆第二医学院,新疆克拉玛依834000 [4]省部共建中亚高发病成因与防治国家重点实验室,新疆乌鲁木齐830011

出　　处：《预防医学》2023年第11期939-942,947,共5页CHINA PREVENTIVE MEDICINE JOURNAL

基　　金：新疆医科大学省部共建国家重点实验室项目(SKL-HIDCA-2020-ER4);新疆医科大学第16期大学生创新项目(CX2021107)。

摘　　要：目的探讨心血管疾病合并肌少症的影响因素,为早期发现和预防心血管疾病合并肌少症提供依据。方法选择新疆生产建设兵团第六师医院住院治疗的250例心血管疾病患者为研究对象,按照肌少症诊断标准纳入肌少症组和非肌少症组,收集基本信息、体质指数(BMI)、血生化指标和人体成分指标等资料。采用多因素logistic回归模型分析心血管疾病合并肌少症的影响因素。结果纳入研究的250例心血管疾病患者中男性149例,占59.60%;女性101例,占40.40%。合并肌少症21例,患病率为8.40%。肌少症组和非肌少症组年龄分别为(75.19±9.74)岁和(65.24±11.50)岁,BMI分别为(20.77±2.19)和(25.85±2.87)kg/m2。多因素logistic回归分析结果显示,年龄(O_(R)=1.115,95%CI:1.030~1.207)和BMI(O_(R)=0.582,95%CI:0.445~0.761)是心血管疾病合并肌少症的影响因素。结论年龄增长、较低BMI可能增加心血管疾病合并肌少症的风险。Objective To investigate the factors affecting concurrent sarcopenia among patients with cardiovascular dis-eases,so as to provide insights into early identification and prevention of cardiovascular diseases complicated with sarco-penia.Methods A total of 250 inpatients with cardiovascular diseases in the Sixth Division Hospital of Xinjiang Pro-duction and Construction Corps were recruited and divided into the sarcopenia and non-sarcopenia groups according to the diagnostic criteria of sarcopenia.Subjects'basic characteristics,body mass index,blood biochemical indicators and human body composition parameters were collected using questionnaire surveys,and factors affecting concurrent sarcope-nia among patients with cardiovascular diseases using a multivariable logistic regression model.Results Among the 250 patients with cardiovascular diseases,there were 149 males(59.60%)and 101 females(40.40%).The overall prevalence of sarcopenia was 8.40%among the study subjects.The mean age and body mass index were(75.19±9.74)and(20.77±2.19)kg/m2 in the sarcopenia group and(65.24±11.50)years and(25.85±2.87)kg/m2 in the non-sarcopenia group.Multi-variable logistic regression analysis identified age(O_(R)=1.115,95%CI:1.030-1.207)and body mass index(O_(R)=0.582,95%CI:0.445-0.761)were as factors affecting concurrent sarcopenia among patients with cardiovascular diseases.Con-clusion Advanced age and low body mass index may increase the risk of concurrent sarcopenia among patients with cardiovascular diseases.

关 键 词：心血管疾病 肌少症 年龄 体质指数 影响因素 

分 类 号：R714.252[医药卫生—妇产科学] R685[医药卫生—临床医学]