古方青娥丸治疗骨质疏松症的研究进展  

Research progress of the ancient formula Qing'e Pill in treating osteoporosis

作　　者：陈世洲 孙鲁宁[1] 曹鲁梅[1] 梅伟[1] 束昊[1] 黄瑶 袁滨[1] 毛国庆[1] CHEN Shizhou;SUN Luning;CAO Lumei;MEI Wei;SHU Hao;HUANG Yao;YUAN Bin;MAO Guoqing(Department of Orthopedics and Traumatology,Hospital of Nanjing University of Chinese medicine,Nanjing,Jiangsu 210029,China)

机构地区：[1]南京中医药大学附属医院骨伤科,江苏南京210029

出　　处：《湖南中医药大学学报》2023年第11期2138-2142,共5页Journal of Hunan University of Chinese Medicine

基　　金：第四批全国中医优秀人才研修项目(J20184832009);江苏省中医传统运动康复技术项目(K2017ykf08);江苏省创新计划工程项目(SJCX19_0405)。

摘　　要：骨质疏松症是一种临床常见的慢性全身性骨骼疾病,其发病率逐年增加,致死率、致残率应引起大家足够的重视。随着国家大力倡导中医药事业的发展,传承创新中医药的共识不断增强,诸如古方青娥丸等一系列传统医药逐渐显现出其独特优势。着重探讨青娥丸治疗骨质疏松症的临床与基础研究,并结合相关可能机制做出综述,能够更好地展现其独特魅力,以期为骨质疏松症的临证诊疗提供参考与借鉴。Osteoporosis is a common chronic systemic skeletal disease in clinic.Since the incidence is increasing year by year,its mortality and disability rate deserve more attention.With the country's vigorous advocation of developing TCM and the continual strengthening of the consensus on inheriting and innovating TCM,a series of traditional medicines,such as the ancient formula Qing'e Pill,have gradually shown their unique advantages.This paper focuses on exploring the clinical and basic research of Qing'e Pill in treating osteoporosis and combines the relevant possible mechanisms to make an overview in order to better demonstrate its unique charm and provide reference for the clinical diagnosis and treatment of osteoporosis.

关 键 词：青娥丸 骨质疏松症 研究进展 作用机制 信号通路 骨形成 骨吸收 

分 类 号：R274[医药卫生—中医骨伤科学]