连云港市无偿献血者梅毒抗体筛查阳性结果分析  

Analysis of positive results of syphilis antibody screening among unpaid blood donors in Lianyungang city

作　　者：张春晓 姚勇[1] ZHANG Chunxiao;YAO Yong(Lianyungang Red Cross Center Blood Station,Lianyungang 222001,China)

机构地区：[1]连云港市红十字中心血站,江苏连云港222001

出　　处：《临床医学研究与实践》2023年第33期10-13,共4页Clinical Research and Practice

摘　　要：目的分析连云港市无偿献血者梅毒螺旋体(TP)抗体阳性结果。方法收集2017年1月1日至2021年12月31日无偿献血者的血液标本205899份。采用两种试剂行酶联免疫吸附法(ELISA)检测,双试剂均有反应性则判定为阳性结果。利用血站业务操作穿越软件系统将献血者按年份、献血次数、人口来源、性别、血型、年龄、学历、职业等基本情况进行分类,分别计算其TP抗体阳性例数与阳性率。结果2017—2021年献血者TP抗体阳性率比较,差异具有统计学意义(P<0.05)。初次献血者TP抗体阳性率为0.59%,明显高于重复献血者的0.01%(P<0.05);本地与外地献血者的TP抗体阳性率无明显差异(P>0.05)。不同性别和血型的献血者TP抗体阳性率无明显差异(P>0.05);不同年龄、学历和职业的献血者TP抗体阳性率比较,差异具有统计学意义(P<0.05)。结论连云港市无偿献血者TP抗体阳性率呈下降趋势,但风险依然存在。在无偿献血宣传招募中,还应宣传输血相关疾病的知识,特别要重视高危人群献血前的健康教育和征询。从低危人群中招募献血者,不断发展固定献血者队伍,提高血液筛查技术水平,降低梅毒经输血传播风险,确保输血安全。Objective To analyze the positive results of treponema pallidum(TP)antibody in unpaid blood donors in Lianyungang city.Methods A total of 205899 blood samples were collected from unpaid blood donors from January 1,2017 to December 31,2021.Two reagents were used for enzyme linked immunosorbent assay(ELISA)detection,and the reactivity of both reagents were determined as positive results.The blood donors were classified according to the basic conditions such as year,number of blood donations,population source,gender,blood type,age,education background and occupation by the blood station business operation crossing software system,and the number of TP antibody positive cases and positive rate were calculated respectively.Results There was a statistically significant difference in the positive rate of TP antibody among blood donors in 2017—2021(P<0.05).The positive rate of TP antibody in first-time blood donors was 0.59%,which was significantly higher than 0.01%in repeated blood donors(P<0.05);there was no significant difference in the positive rate of TP antibody between local and non-local blood donors(P>0.05).There were no significant differences in the positive rates of TP antibody among blood donors of different gender and blood type(P>0.05);there were statistically significant differences in the positive rates of TP antibody among blood donors of different age,education background and occupation(P<0.05).Conclusion The positive rate of TP antibody in unpaid blood donors in Lianyungang city showed a downward trend,but the risk still existed.In the recruitment of unpaid blood donation,we should publicize the knowledge of blood transfusion-related diseases,pay special attention to the health education and consultation before blood donation in high-risk groups,recruit blood donors from low-risk groups,continuously develop a fixed blood donor team,improve the level of blood screening technology,reduce the risk of syphilis transmission through blood transfusion,and ensure the safety of blood transfusion.

关 键 词：无偿献血者 梅毒螺旋体 阳性率 

分 类 号：R446.6[医药卫生—诊断学]