中药复方颗粒湿敷联合重组人表皮生长因子凝胶治疗面部脂溢性皮炎临床观察  

Chinese Herbal Compound Granule Wet Compress Combined with Recombinant Human Epidermal Growth Factor Gel in the Treatment of Facial Seborrheic Dermatitis

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作  者:秦倩 QIN Qian(Dermatology Department,Luocun Hospital of Nanhai District,Guangdong Province,Foshan 528226,China)

机构地区:[1]佛山市南海区罗村医院皮肤科,广东佛山528226

出  处:《中国中医药现代远程教育》2023年第24期143-145,共3页Chinese Medicine Modern Distance Education of China

摘  要:目的探讨中药复方颗粒湿敷联合重组人表皮生长因子(rh-EGF)凝胶治疗面部脂溢性皮炎(SD)的临床效果及安全性。方法选取佛山市南海区罗村医院2021年4月—2021年10月收治的60例面部SD患者,按随机数字表法分为对照组和观察组,各30例。对照组予以口服盐酸多西环素片、地氯雷他定片加rh-EGF凝胶治疗,观察组在对照组用药基础上加用中药复方颗粒湿敷治疗,持续用药2周。比较2组治疗效果。结果观察组总有效率93.33%(28/30)较对照组的73.33%(22/30)高,差异有统计学意义(P<0.05);观察组治疗后皮损面积、红斑、鳞屑及瘙痒评分和皮肤病生活质量指数(DLQI)低于对照组,差异有统计学意义(P<0.05);2组不良反应发生率对比,差异无统计学意义(P>0.05)。结论中药复方颗粒湿敷联合rh-EGF凝胶可提高面部SD的治疗效果,加快皮损、瘙痒等症状消失,改善患者生活质量,安全可靠。Objective To investigate the clinical effect and safety of Chinese herbal compound granule compress combined with recom⁃binant human epidermal growth factor(rh-EGF)gel in the treatment of facial seborrheic dermatitis(SD).Methods Sixty patients with facial SD admitted to Luocun Hospital of Nanhai District from April 2021 to October 2021 were selected and divided into two groups ac⁃cording to random number table method,with 30 cases in each group.The control group was treated with oral doxycycline and deslorata⁃dine tablets and rh-EGF gel,while the observation group was treated with Chinese herbal compound granule wet compress on the basis of the control group.The treatment continued for 2 weeks.The therapeutic effects of the two groups were compared.Results The total ef⁃fective rate of observation group was 93.33%(28/30),which was higher than that of control group(73.33%,22/30),and the difference was statistically significant(P<0.05).After treatment,the skin area,erythema,scale and pruritus scores and skin quality of life index(DLQI)of the observation group were lower than those of the control group,and the differences were statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Chinese herbal compound granule compress combined with rh-EGF gel can improve the therapeutic effect of facial seborrheic dermatitis,accelerate the disappearance of symptoms such as skin lesions and pruritus,and improve the quality of life of patients,which is safe and reliable.

关 键 词:面游风 面部脂溢性皮炎 中药复方颗粒 重组人表皮生长因子凝胶 

分 类 号:R758.732[医药卫生—皮肤病学与性病学]

 

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