糖尿病视网膜病变中医证型规律研究  

A study on traditional Chinese medicine syndrome pattern of diabetic retinopathy

作　　者：边云[1] 田风胜[1] BIAN Yun;TIAN Fengsheng

机构地区：[1]河北省沧州中西医结合医院,河北沧州061000

出　　处：《中医临床研究》2023年第27期84-88,共5页Clinical Journal Of Chinese Medicine

基　　金：河北省中医药管理局2021年度省级中医药类科研计划项目(2021337)。

摘　　要：目的:探讨2型糖尿病(Type 2 Diabetes Mellitus,T2DM)合并视网膜病变患者中医证型分布规律。方法:选取2020年1月―5月在河北省沧州中西医结合医院内分泌科住院的180例T2DM患者,采用糖尿病视网膜病变(Diabetic Retinopathy,DR)诊断标准将患者分为DR0期组63例,非增殖期糖尿病视网膜病变(Non-proliferative Diabetic Retinopathy,NPDR)组99例,增殖期糖尿病视网膜病变(Proliferative diabetic retinopathy,PDR)组18例。收集三组患者的病例资料,比较其中医证型的分布情况。结果:阴虚热盛证和痰湿郁热证两组的DR患病率比较,差异无统计学意义(P> 0.008 3);气阴两虚证和阴阳两虚证两组的DR患病率比较,差异无统计学意义(P> 0.008 3);阴虚热盛证组和痰湿郁热证组DR患病率低于气阴两虚证组和阴阳两虚证组,差异有统计学意义(P<0.008 3)。病程<5年、病程5~10年、病程>10年三组的中医证型分布比较,差异有统计学意义(P<0.05)。阴虚热盛证、痰湿郁热证、气阴两虚证、阴阳两虚证四组的DR分期比较差异有统计学意义(P <0.05)。结论:T2DM患者中气阴两虚证和阴阳两虚证DR患病率最高,不同病程中医证型分布存在差异,不同中医证型DR分期亦不同,随着病程的延长,中医证型出现由阴虚热盛证、痰湿郁热证向气阴两虚证、阴阳两虚证的过渡,视网膜病变的程度逐渐加重。Objective:To investigate the distribution of TCM syndrome types in type 2 diabetes mellitus(T2DM)patients with retinopathy.Methods:A total of 180 T2DM patients hospitalized in Department of Endocrinology,Cangzhou Hospital of Integrated Traditional and Western Medicine from January 2020 to May 2020 were selected.According to the diagnostic criteria of diabetic retinopathy (DR), the patients were divided into DR0 group (63 cases), non-proliferative diabetic retinopathy (NPDR) group (99 cases), and proliferative diabetic retinopathy (PDR) group (18 cases). The case data of patients in the three groups was collected and the distribution of TCM syndrome types was compared. Results: There was no significant difference in the prevalence of DR between Yin ( 阴) deficiency and heat excess syndrome and phlegm-dampness-stagnation heat syndrome (P>0.008 3). There was no significant difference in the prevalence of DR between Qi ( 气) and Yin deficiency syndrome and Yin and Yang ( 阳) deficiency syndrome (P>0.008 3). The prevalence of DR in Yin deficiency and heat excess syndrome group and phlegm-dampness-stagnation heat syndrome group was lower than that in Qi and Yin deficiency syndrome group and Yin and Yang deficiency syndrome group, and the difference was statistically significant (P<0.008 3). There was a statistical significance in the distribution of TCM syndrome types among the three groups with disease course <5 years, disease course 5-10 years and disease course >10 years (P<0.05). There were significant differences in DR staging between Yin deficiency and heat excess syndrome, phlegm-dampness and heat stagnation syndrome, Qi and Yin deficiency syndrome and Yin and Yang deficiency syndrome (P<0.05). Conclusion: In T2DM patients, the prevalence rate of DR in Qi and Yin deficiency syndrome and Yin and Yang deficiency syndrome is the highest, and the distribution of TCM syndrome types is different in different disease course, and the stages of DR are also different in different TCM syndrome types. With the extension

关 键 词：糖尿病视网膜病变 2型糖尿病 中医证型 病程 

分 类 号：R587.1[医药卫生—内分泌]