磁共振成像增强肝胆期不同病理分级肝内肿块型胆管癌的信号特征分析  

Analysis of signal characteristics of intrahepatic mass-forming cholangiocarcinoma with different pathologic grades in enhanced-MRI hepatobiliary phase

作　　者：殷小平[1] 邢立红 卓利勇 张宇[1] 王佳宁[1] 刘珊 陈新星 YIN Xiaoping;XING Lihong;ZHUO Liyong;ZHANG Yu;WANG Jianing;LIU Shan;CHEN Xinxing(Department of Radiology,Affiliated Hospital of Hebei University,Baoding 071000,China)

机构地区：[1]河北大学附属医院放射科,河北保定071000

出　　处：《医学研究与教育》2023年第5期1-7,共7页Medical Research and Education

基　　金：河北省“三三三人才工程”项目(B20031008);保定市科学技术研究与发展计划项目(2041ZF176)。

摘　　要：目的探讨MRI增强肝胆期信号特征与肝内肿块型胆管癌(intrahepatic mass cholangiocarcinoma,IMCC)病理分级的关系。方法回顾性分析IMCC确诊患者,分析病灶肝胆期的信号特征。统计学分析采用卡方检验。结果IMCC确诊患者共49例,高分化5例,中分化26例,低分化18例。病灶长径<3 cm者11例,3~6 cm者18例,>6 cm者20例。肝胆期出现靶征者21例,多层靶征20例,低信号8例。肝胆期病灶外周低信号环存在41例,其中环完整20例,不完整21例。病灶大小在不同肝胆期信号间、低信号环是否完整在不同病理间的差异有统计学意义(χ^(2)=18.937,P=0.001;χ^(2)=6.618,P=0.037)。结论肝胆期病灶外周低信号环不完整多见于低分化IMCC,病灶越大者越多呈分层靶征。Objective To investigate the relationship between signal characteristics in enhanced-MRI hepatobiliary phase(HBP)and pathological grade of intrahepatic mass cholangiocarcinoma(IMCC).Methods Patients diagnosed with IMCC were retrospectively analyzed,and the signal characteristics of lesions in HBP were analyzed.Statistical analysis was performed by Chi-square test.Results 49 patients were diagnosed with IMCC.There were 5 cases with well-differentiated,26 cases with moderately-differentiated and 18 cases with poorly-differentiated.11 patients with lesion length less than 3 cm;18 patients with lesion length between 3 cm and 6 cm,20 patients with lesion length more than 6 cm.In HBP,21 patients had target sign,20 patients had multilayer target sign,and 8 patients had low signal.41 cases had peripheral low.The difference of lesion size between different signal in HBP,and the difference of peripheral low signal ring integrity between different pathological grades were statistically significant(χ^(2)=18.937,P=0.001;χ^(2)=6.618,P=0.037).Conclusion Incomplete peripheral low signal ring in HBP is more common in poorly-differentiated IMCC,and the larger the lesion is,the more it shows multilayer target sign.

关 键 词：磁共振成像 肿块型胆管癌 肝胆期 病理分级 

分 类 号：R54[医药卫生—心血管疾病]