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作 者:金诗萍 孙莹[1] 张雪勤[1] Shiping Jin;Ying Sun;Xueqin Zhang(College of Chemistry and Chemical Engineering,Southeast University,Nanjing 211189,China)
出 处:《化学进展》2023年第9期1304-1312,共9页Progress in Chemistry
基 金:国家自然科学基金面上项目(No.22275035);江苏省重点研发计划(No.BE 2022025⁃2)资助。
摘 要:近年来,水凝胶在角膜接触镜和医用敷料等生物医学领域得到广泛应用。在这些领域中,透氧性能是衡量水凝胶材料应用性能的关键性指标。本文概述了传统聚合物水凝胶和硅水凝胶在角膜接触镜和医用敷料领域的应用,分别总结了传统水凝胶和硅水凝胶在结构设计及透氧机理方面的研究进展,重点分析了影响硅水凝胶透氧性能的各种因素。希望通过对近期相关研究工作的总结和梳理,能更加深入地理解水凝胶微观结构与透氧性能之间的关系,为调控材料性能和设计出满足需求的材料提供帮助。In recent years,hydrogels have been widely used in biomedical fields such as contact lenses and medical dressings.In these fields,oxygen permeability is a key index to evaluate the application performance of hydrogel materials.In this paper,the application of traditional hydrogels and silicone hydrogels in the field of corneal contact lenses and medical dressings is sketched.The research progress of traditional hydrogels and silicone hydrogels in structural design and oxygen permeability mechanism is summarized,and various factors affecting the oxygen permeability of silicone hydrogels are analyzed emphatically.It is hoped that the relationship between hydrogel microstructure and oxygen permeability can be further understood by summarizing and sorting out the recent related research work,so as to provide help for the regulation of material properties and the design of materials to meet the requirements.
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