肺炎支原体肺炎合并皮疹患儿临床特点分析  

Analysis of clinical characteristics of children with Mycoplasma pneumoniae pneumonia combined with skin rash

作　　者：王怡 姚欢银[2] WANG Yi;YAO Huan-yin(Shaoxing University,Shaoxing,Zhejiang 312000,China)

机构地区：[1]绍兴文理学院医学院,浙江绍兴312000 [2]绍兴市人民医院

出　　处：《中国妇幼保健》2023年第22期4357-4360,共4页Maternal and Child Health Care of China

基　　金：浙江省医药卫生一般研究计划项目A类(2015KYA219)。

摘　　要：目的分析肺炎支原体肺炎(MPP)合并皮疹患儿的临床特点及危险因素,提高对其的诊治水平。方法回顾性收集自2018年12月—2021年12月绍兴市人民医院的肺炎支原体肺炎合并皮疹的13例患儿临床资料。肺炎支原体肺炎合并皮疹的13例患儿作为皮疹组,普通支原体肺炎未合并皮疹的36例患儿作为无皮疹组,比较两组患儿的一般资料(性别、年龄、发病季节)、临床表现及实验室检查结果。结果皮疹组患儿的白细胞总数、血清乳酸脱氢酶、糖皮质激素使用率、吸氧治疗率、支气管镜介入率、住院费用及重症比例高于无皮疹组患儿,差异有统计学意义(t=2.616、3.310;χ^(2)=10.548、14.687;t=2.631,均P<0.05)。皮疹组患儿中皮疹形态呈多形性,其中以非特异性的斑疹和斑丘疹(76.9%)最常见。通过logistic回归分析筛选出LDH为独立危险因素。结论皮疹组患儿吸氧率、支气管镜介入率、免疫球蛋白使用率及重症比例和糖皮质激素使用率较高,对疾病严重程度有一定提示意义,但总体预后良好。Objective To analyze the clinical characteristics and risk factors of children with Mycoplasma pneumoniae pneumonia(MPP)combined with rash,and to improve the diagnosis and treatment of them.Methods The clinical data of 13 children with Mycoplasma pneumoniae pneumonia combined with rash in Shaoxing People's Hospital from December 2018 to December 2021 were retrospectively collected.The 13 children with Mycoplasma pneumoniae pneumonia combined with rash(rash group)were compared with 36 children with common mycoplasma pneumonia without rash(no rash group),and the general data(gender,age,season of onset),clinical manifestations,and laboratory test results of the two groups were compared.Results The total leukocyte count,serum lactate dehydrogenase,glucocorticoid use rate,oxygen therapy rate,bronchoscopic intervention rate,hospitalization cost and proportion of serious illness were higher in the children in the rash group than in the children in the no-rash group,with statistically significant differences(t=2.616,3.310;χ^(2)=10.548,14.687;t=2.631,all P<0.05).The rash pattern was polymorphic among the children in the rash group,with nonspecific macular rash and maculopapular rash(76.9%)being the most common.LDH was screened as an independent risk factor by logistic regression analysis.Conclusion The higher rates of oxygenation,bronchoscopic intervention,immunoglobulin use and proportion of severe disease and glucocorticoid use in children in the rash group were suggestive of disease severity,but the overall prognosis was good.

关 键 词：肺炎支原体肺炎 儿童 皮疹 

分 类 号：R725.65[医药卫生—儿科]