BDD电极修饰及其在生物传感器中的应用进展  

Modification of BDD electrode and its application progress in biosensor

作　　者：刘立娜 马雪姣 韩严和[1] 徐晗 王楠楠 LIU Li’na;MA Xuejiao;HAN Yanhe;XU Han;WANG Nannan(Department of Environmental Engineering,Beijing Institute of Petrochemical Technology,Beijing 102617,China)

机构地区：[1]北京石油化工学院环境工程系,北京102617

出　　处：《工业水处理》2023年第11期66-77,共12页Industrial Water Treatment

基　　金：国家自然科学基金项目(21677018);北京市自然科学基金-市教委联合项目(KZ2018100117024);北京石油化工学院交叉科研探索项目(BIPTCSF-22032205003/014)。

摘　　要：生物传感器已被广泛应用于对痕量有机物和生物大分子等物质的检测中,提高生物传感器的检测准确性、检测范围、灵敏度等检测性能是近年来的重点研究内容。掺硼金刚石(BDD)电极基于其优异的物化性质,是目前生物传感器理想的基底材料之一,但其存在价格昂贵、传感性能不高等问题,而化学修饰是提高BDD电极传感性能的有效途径。系统论述了吸附法、共价键结合法和电沉积法3种当前主流的BDD基底修饰方法,在阐述其反应机理的基础上,总结了不同方法所修饰的BDD电极在生物传感器中的应用,并深入分析了各修饰方法的优势和不足。最后,总结了BDD电极作为基底材料应用于生物传感器领域中存在的问题,并展望了未来的重点发展方向,以期为BDD电极的修饰和潜在的实际应用提供新思路。Biosensors have been widely used in the detection of trace organic matter and biological macromolecules.The improvement of detection performance of biosensors,such as accuracy,detection range and sensitivity,is the focus of study in recent years.Boron-doped diamond(BDD)electrode,based on its excellent physico-chemical property,is one of the ideal substrate materials for biosensors.However,BDD electrode has also some drawbacks such as high price and low sensing capacity which can be improved efficiently by chemical modification.Herein,three main modification methods of BDD substrate,including adsorption,covalent bonding and electrodeposition method,were systematically discussed.Based on the description of their reaction mechanisms,the application of BDD electrode modified by different methods in biosensor was summarized,and the advantages and disadvantages of each modification method were deeply analyzed.Finally,the problems in the application of BDD electrodes as substrate materials in the field of biosensors were summarized,and the main development directions were prospected.It is hoped to provide new ideas for the modification and potential practical application of the BDD electrode.

关 键 词：掺硼金刚石电极 表面修饰 生物传感器 复合材料 

分 类 号：TQ050.4[化学工程] X703[环境科学与工程—环境工程]