Activating weak electrophiles to break nonpolar C-C bonds with electric fields  

作　　者：Xueyan Zhao Adila Adijiang Dong Xiang 

机构地区：[1]Institute of Modern Optics and Center of Single-Molecule Science,Tianjin Key Laboratory of Micro-scale Optical Information Science and Technology,Nankai University,Tianjin 300350,China [2]School of Materials Science and Engineering,Smart Sensing Interdisciplinary Science Center,Nankai University,Tianjin 300350,China

出　　处：《Chinese Chemical Letters》2023年第11期1-2,共2页中国化学快报（英文版）

摘　　要：Electrophilic aromatic substitution(EAS)is a vital chemical reaction in organic chemistry that involves replacing substituent on an aromatic ring by an electrophile.Despite its widespread industrial applications in the production of substituted aromatic compounds,the reaction typically requires harsh reaction conditions,such as high temperature and potent Lewis acid catalysts,to activate the electrophile due to the stability of the aromatic ring[1].Recently,a study published by Yaping Zang and colleagues in Nature Communications demonstrates the use of an electric field as a catalyst to regulate EAS reactivity,replacing conventional chemical reagents.The research team discovered that an electric field could activate an otherwise unreactive electrophile and break inert nonpolar C-C bonds under mild conditions.These unprecedented results showcase the potential for broadening the scope of EAS reactions via electric field catalysis.

关 键 词：BONDS AROMATIC polar 

分 类 号：O62[理学—有机化学]