Recent advances of Pd-π-allyl zwitterions in cycloaddition reactions  

作　　者：Juan Du Yun-Fan Li Chang-Hua Ding 

机构地区：[1]Guangxi Key Laboratory of Natural Polymer Chemistry and Physics,College of Chemistry and Materials,Nanning Normal University,Nanning 530001,China [2]Department of Chemistry,Shanghai Engineering Research Center of Organ Repair,Innovative Drug Research Center,Shanghai University,Shanghai 200444,China

出　　处：《Chinese Chemical Letters》2023年第11期3-19,共17页中国化学快报（英文版）

基　　金：the financial support from the National Natural Science Foundation of China(Nos.22071143 and 21772215);Start-up Funding for Scientific Research of Nanning Normal University(No.86612345);“BAGUI Scholar”Program of Guangxi Province of China。

摘　　要：Palladium-catalyzed cycloaddition reactions via Pd-π-allyl zwitterions have been established as significant synthetic transformations to enable numerous carbon-or heterocycles compounds that are key constituents of various biologically active natural products and pharmaceuticals.In addition to the well-known Pd-π-allyl zwitterions,including palladium-trimethylenemethane and Pd-1,3/1,4-zwitterions,chemists have recently discovered new applications of several long ago reported but less-studied Pd-π-allyl zwitterions,which can straightforwardly and efficiently construct novel cyclic architectures.Meanwhile,some impressive newly designed zwitterions have been also developed.Those zwitterions are diverse and can serve as transient and highly reactive intermediates for the subsequent cyclization with various acceptors.In this review,we highlight recent advances in applications of these two types of zwitterions in the synthesis of complex polycyclics and medium-sized cyclic compounds.

关 键 词：Palladium CYCLOADDITION Pd-π-allyl zwitterions Asymmetric catalysis HETEROCYCLES 

分 类 号：O62[理学—有机化学]