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作 者:樊慧峰[1] 卢根[1] Fan Huifeng;Lu Gen(Department of Respiration,Guangzhou Women and Children′s Medical Center,Guangzhou Medical University,Guangzhou 510623,China)
机构地区:[1]广州医科大学附属广州市妇女儿童医疗中心呼吸科,广州510623
出 处:《中华实用儿科临床杂志》2023年第11期833-837,共5页Chinese Journal of Applied Clinical Pediatrics
基 金:广东省基础与应用基础研究基金项目(2021A1515010116)。
摘 要:腺病毒肺炎是儿童常见的呼吸道感染,重症患儿具有起病急、进展快、并发症多的特点,因此早期识别与诊断尤为重要。近年来从病原、宿主、实验室检查及生物标志物等多方面进行了研究,为儿童重症腺病毒肺炎早期识别与诊断提供了新的临床线索。目前尚无用于重症腺病毒肺炎的特效抗病毒药物,主要治疗策略为免疫调节及呼吸支持,大量临床研究为规范治疗策略、改善患儿预后提供了新的思路。Adenovirus pneumonia is a common respiratory tract infection in children.Severe cases of adenovirus pneumonia have the characteristics of rapid onset,rapid progression and a panel of complications.Therefore,early recognition,diagnosis and treatment are particularly important.In recent years,studies on the pathogens,hosts,laboratory tests and biomarkers have provided new clinical clues for the early recognition and diagnosis of severe adenovirus pneumonia in children.There are currently no specific antiviral drugs for severe adenovirus pneumonia.Therefore,the main therapeutic strategies for adenovirus pneumonia are immune therapy and respiratory support.A large number of clinical studies have provided new ideas for standardizing therapeutic strategies and improving the prognosis of children.
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