经-穴体外反搏治疗射血分数保留心力衰竭临床研究  

Clinical Study of Meridian-Point External Counter-Pulsation for Heart Failure with Preserved Ejection Fraction

作　　者：李双妍 李建功 李雪山 LI Shuangyan;LI Jiangong;LI Xueshan(Zhongshan Hospital of Chinese Medicine Affiliated to Guangzhou University of Chinese Medicine,Zhongshan Guangdong 528400,China)

机构地区：[1]广州中医药大学附属中山中医院,广东中山528400

出　　处：《新中医》2023年第19期172-175,共4页New Chinese Medicine

基　　金：中山市卫生健康局科研项目(2021J143)。

摘　　要：目的:观察经-穴体外反搏治疗射血分数保留心力衰竭的临床疗效。方法:选取射血分数保留心力衰竭患者72例,采用随机数字表法分为对照组和试验组各36例,治疗过程中对照组脱落4例,试验组脱落5例。对照组给予西医规范化治疗,试验组在对照组基础上给予经-穴体外反搏治疗。比较2组治疗前后中医证候积分、N-末端脑利钠肽前体(NT-pro BNP)水平,检测心肌收缩指数(ICON)、心输出量(CO)、心脏指数(CI)。结果:治疗后,2组中医证候积分较治疗前降低(P<0.05),且试验组中医证候积分低于对照组(P<0.05)。治疗后,2组NT-pro BNP水平较治疗前降低(P<0.05);且试验组NT-pro BNP水平低于对照组(P<0.05)。治疗后,2组ICON、CO、CI较治疗前升高(P<0.05);且试验组ICON、CO、CI高于对照组(P<0.05)。结论:经-穴体外反搏治疗射血分数保留心力衰竭能改善临床症状,降低NT-pro BNP水平,改善心肌收缩功能。Objective:To observe the clinical effect of meridian-point external counter-pulsation on heart failure with preserved ejection fraction.Methods:A total of 72 patients with heart failure with preserved ejection fraction were selected and divided into the control group and the trial group according to the random number table method,with 36 cases in each group.During the treatment,4 cases were dropped off in the control group and 5 cases in the trial group.The control group was given the standard treatment in western medicine,and the trial group was additionally treated with meridian-point external counter-pulsation based on the treatment of the control group.Before and after treatment,the traditional Chinese medicine syndrome(TCM) scores and the levels of N terminal pro B type natriuretic peptide(NT-pro BNP) were compared between the two groups;the index of contractility(ICON),cardiac output(CO)and cardiac index(CI) in both groups were detected.Results:After treatment,the TCM syndrome scores in the two groups were decreased when compared with those before treatment(P<0.05),and the TCM syndrome scores in the trial group was lower than that in the control group(P<0.05).After treatment,the NT-pro BNP levels in both groups were decreased when compared with those before treatment(P<0.05);the NT-pro BNP level in the trial group was lower than that in the control group(P<0.05).After treatment,the ICON,CO and CI in both groups were increased when compared with those before treatment(P<0.05);the ICON,CO and CI in the trial group were higher than those in the control group(P<0.05).Conclusion:The meridian-point external counter-pulsation can improve the clinical symptoms of patients with heart failure with preserved ejection fraction,reduce the NT-pro BNP level and enhance the myocardial contraction function.

关 键 词：射血分数保留心力衰竭 经-穴体外反搏 无创心排量 中医证候积分 N-末端脑利钠肽前体 

分 类 号：R541.6[医药卫生—心血管疾病]