大头瘟疫古今病名考及其临床应用价值分析  

Examination of the Ancient and Modern Names of Epidemic Infection with Swollen Head and Its Clinical Application Value Analysis

作　　者：侯雪雍 刘龙坤 陈宣妤 赵一霖 刘绍媛 赵岩松[1] Hou Xueyong;Liu Longkun;Chen Xuanyu;Zhao Yilin;Liu Shaoyuan;Zhao Yansong(Beijing University of Chinese Medicine,Beijing 100029,China)

机构地区：[1]北京中医药大学,北京100029

出　　处：《中国中医急症》2023年第11期1920-1926,共7页Journal of Emergency in Traditional Chinese Medicine

基　　金：国家社会科学基金项目“清代中医疫病学发展知识图谱构建研究”(22BZS077);国家中医药管理局中医药创新团队及人才支持计划项目(ZYYCXTD-C-202006)。

摘　　要：目的 通过考证大头瘟病名古今源流,探讨大头瘟与现代临床疾病的关系,总结古代医家治疗大头瘟用药规律与现代应用价值。方法 梳理大头瘟病名形成脉络,总结具有相似临床表现的现代疾病,整理古籍中有关大头瘟的方药记载数据,导入Neo4j构建图数据库,导入古今医案云平台进行中药频次统计、中药属性分析、关联分析、聚类分析及复杂网络分析。结果 发现古代医家认识大头瘟以风热毒火上攻头面为主要病机;基本治则为清热泻火、凉血解毒、疏风散结;用药以苦寒佐辛凉为主;银翘散、桔梗汤、普济消毒饮合增损双解散为核心方义。结论 古今医家对大头瘟疫的认识始于隋唐,完善于明清,借助知识图谱可得出不同古籍大头瘟治疗思路共识,指导当今临床治疗以风热毒火上攻头面为核心病机,以头面部红肿热痛,并伴有发热、身痛等全身症状的疾病,如鼠疫、组织细胞坏死性淋巴结炎、流行性腮腺炎、颜面丹毒、睑腺炎等。Objective:To examine the ancient and modern origin of the disease name of epidemic infection with swollen head,to investigate the relationship between the ancient disease and modern clinical diseases,and to sum⁃marize the prescription rules and modern application values of ancient healers for the treatment of epidemic infec⁃tion with swollen head.Methods:Data were collected from the ancient texts on the prescriptions and medicines of the disease,and the results were imported into Neo4j to build a graphical database,and imported into the an⁃cient and modern medical case cloud platform to conduct frequency statistics,attribute analysis,association analy⁃sis,cluster analysis and complex network analysis on the recorded prescriptions and medicines,and to export the visualization results.Results:It was found that the ancient medical practitioners considered that the main patho⁃genesis of the disease was wind-heat and poisonous fire attacking the head and face,and the basic treatment was to clear heat and fire,cool the blood and detoxify the toxin,and disperse wind and nodules,and Yinqiao Powder,Jiegeng Decoction,Puji Xiaodu Decoction,and Zengsun Shuangjie Powder were the core formulas.Conclusion:The understanding of the swollen head by ancient and modern physicians began in the Sui and Tang dynasties,and they were perfected in the Ming and Qing dynasties.With the help of the knowledge map,the consensus of the treatment ideas of different ancient books can be obtained,so as to guide the current clinical treatment of dis⁃eases with wind,heat,toxin and fire as the core pathogenesis,redness,with symptoms of swelling,heat and pain of the head and face,accompanied by systemic symptoms of fever and body pain,such as plague,histicytic necrotiz⁃ing lymphadenitis,mumps,facial erysipelas,blepharitis,etc.

关 键 词：大头瘟 源流考证 知识图谱 用药规律 数据挖掘 现代应用 Neo4j 古今医案云平台 

分 类 号：R254.3[医药卫生—中医内科学]