GeneXpert MTB/RIF Ultra在肺外结核诊断中的研究进展  

Progress of diagnosis of extrapulmonary tuberculosis with GeneXpert MTB/RIF Ultra

作　　者：董裕 张福真 尚媛媛[1] 逄宇 Dong Yu;Zhang Fuzhen;Shang Yuanyuan;Pang Yu(Department of Bacteriology and Immunology,Beijing Chest Hospital,Capital Medical University,Beijing 101149,China)

机构地区：[1]首都医科大学附属北京胸科医院细菌免疫研究室,北京101149

出　　处：《中国防痨杂志》2023年第12期1193-1197,共5页Chinese Journal of Antituberculosis

基　　金：北京市高层次公共卫生技术人才建设项目(学科带头人-02-26)

摘　　要：肺外结核是结核病的一种类型,其感染途径和感染部位多样,临床表现复杂,缺乏特异性诊断。目前,病原学和免疫学诊断方法存在弊端,临床亟需能够快速准确诊断肺外结核的实验室方法,以满足早期诊断的需求,配合临床及时开展治疗。GeneXpert MTB/RIF Ultra(简称“Xpert Ultra”)作为一种新型的分子诊断工具,为肺外结核的快速精准诊断开启了新篇章。笔者对Xpert Ultra在各类肺外结核不同标本类型中的诊断效能进行综述,旨在评价其应用价值,为肺外结核诊断提供新思路。Extrapulmonary tuberculosis is a form of tuberculosis characterized by various infection routes and sites,complex clinical manifestations,and a lack of specific diagnosis.Currently,there are limitations in etiological and immunological diagnostic methods,and there is an urgent need for laboratory techniques that can quickly and accurately diagnose extrapulmonary tuberculosis to facilitate early detection and timely treatment.GeneXpert MTB/RIF Ultra(Xpert Ultra)is a novel molecular diagnostic tool that has revolutionized the rapid and precise diagnosis of extrapulmonary tuberculosis.The author examines the diagnostic effectiveness of Xpert Ultra in different types of extrapulmonary tuberculosis specimens,aiming to assess its clinical value and offer new insights into the diagnosis of extrapulmonary tuberculosis.

关 键 词：分子诊断技术 结核 诊断 

分 类 号：R52[医药卫生—内科学] R378.91[医药卫生—临床医学]