试钛灵-铁(Ⅲ)配合物褪色分光光度法测定安乃近片剂含量  

Assay Determination of Analgin in Tablets with Fe(Ⅲ)-Tiron Complexes Fading Photometric Method

作　　者：刘禹含 卢瑶 孙陈磊 朱小米 马卫兴 Liu Yuhan;Lu Yao;Sun Chenlei;Zhu Xaomi;Ma Weixing(School of Pharmacy,Jiangsu Ocean University,Jiangsu Lianyungang 222005;School of Biomedical Industry,Jiangsu Ocean University,Jiangsu Lianyungang 222005)

机构地区：[1]江苏海洋大学药学院,江苏连云港222005 [2]江苏海洋大学生物医药产业学院,江苏连云港222005

出　　处：《化工时刊》2023年第5期20-23,共4页Chemical Industry Times

基　　金：2020年江苏省大学生创新训练项目(一般项目,SY20201164319006)。

摘　　要：基于安乃近可将三价铁离子还原为二价铁离子,剩余三价铁离子再与试钛灵(钛铁试剂)发生配位反应形成绿色配合物,提出试钛灵-铁(Ⅲ)配合物褪色分光光度法测定安乃近含量的新方法。在测定波长660 nm,安乃近浓度的线性范围在2.5~40.0 mg·L^(-1)。本方法成功地测定了安乃近片剂的含量,与碘量法所测结果一致。Based on the reaction of analgin with Fe 3+,and the color complex reaction of the remaining Fe 3+with tiron(Ferrotitarium reagent),the new fading photometric method was proposed for determination of analgin.The determined wavelength is at 660 nm with the linear range at the analgin concentration range of 2.5-40.0 mg·L^(-1).The proposed method was successfully determined the content of analgin tablets in accordance with the determination data of iodometric method.

关 键 词：安乃近 三价铁离子 试钛灵 褪色分光光度法 片剂 

分 类 号：O657.32[理学—分析化学]