2016-2020年乌鲁木齐市梅毒感染孕产妇的治疗情况及影响因素分析  

The treatment and influencing factors of lying-in women infected with syphilis in Urumqi City from 2016 to 2020

作　　者：代玲丽 贾新朝 孙尚贤 王磊 DAI Lingli;JIA Xinzhao;SUN Shangxian;WANG Lei(Shihezi University School of Medicine,Shihezi 832000,Xinjiang,China;Urumqi Maternal and Child Health Care Hospital,Urumqi 830000,Xinjiang,China;School of Public Health,Xinjiang Medical University,Urumqi 830000,Xinjiang,China)

机构地区：[1]石河子大学医学院,新疆维吾尔自治区石河子832000 [2]乌鲁木齐市妇幼保健院,乌鲁木齐830000 [3]新疆医科大学公共卫生学院,乌鲁木齐830000

出　　处：《中国艾滋病性病》2023年第9期1009-1014,共6页Chinese Journal of Aids & STD

摘　　要：目的分析2016-2020年乌鲁木齐市梅毒感染孕产妇妊娠期接受治疗情况并探讨其影响因素。方法利用全国“预防艾滋病、梅毒和乙肝母婴传播信息管理系统”,收集2016-2020年已分娩的梅毒感染孕产妇基本情况和妊娠梅毒治疗情况,采用单因素分析和多因素非条件Logistic回归分析妊娠梅毒治疗和规范治疗的影响因素。结果本研究共纳入符合研究标准的梅毒感染孕产妇421人,其中接受治疗的有217人(51.54%),接受规范治疗的有109人(25.89%)。2016-2020年,梅毒感染孕产妇的治疗率由29.79%上升至93.85%(χ_(趋势)^(2)=64.451,P<0.001),规范治疗率由7.45%上升至52.31%(χ_(趋势)^(2)=48.877,P<0.001)。多因素分析发现,家务及待业(OR=1.623,95%CI:1.020~2.582)、既往存在不良妊娠史(OR=1.682,95%CI:1.067~2.650)、孕早/中期诊断妊娠梅毒(OR=2.688,95%CI:1.712~4.220)、丈夫/性伴侣感染梅毒(OR=2.993,95%CI:1.216~7.366)是梅毒感染孕产妇接受治疗的促进因素,孕早/中期诊断妊娠梅毒(OR=4.464,95%CI:2.534~7.864)、丈夫/性伴侣未感染梅毒(OR=2.982,95%CI:1.731~5.139)是梅毒感染孕产妇接受规范治疗的促进因素。结论乌鲁木齐市梅毒感染孕产妇的治疗率和规范治疗率呈现逐年上升的趋势,治疗率已达到国家要求,但规范治疗率与国家要求还有一定差距。建议乌鲁木齐市采取措施加强孕早中期梅毒的检测力度、促进阳性孕产妇配偶梅毒检测,对从事家务及待业以外其他职业和既往无不良妊娠史的阳性孕产妇加强健康宣教,争取早日实现消除梅毒母婴传播的工作目标。Objective To analyze the treatment situation of syphilis infected lying-in women during pregnancy in Urumqi from 2016 to 2020,and to explore the influencing factors.Methods The national"Information Management System for the Prevention of Mother-to-Child Transmission of AIDS,Syphilis and hepatitis B"was used to collect the basic information of syphilis infected women who had given birth,and the data of syphilis treatment situation during pregnancy from 2016 to 2020.Single factor analysis and multifactor unconditional logistic regression were used to analyze the influencing factors of syphilis treatment in pregnancy and the standardized treatment.Results A total of 421 syphilis infected lying-in women who met the research criteria were enrolled,of which,217(51.54%)received treatment and 109(25.89%)received standardized treatment.From 2016 to 2020,the treatment rate of syphilis infected pregnant women increased from 29.79%to 93.85%(χ_(trend)^(2)=64.451,P<0.001),and the standardized treatment rate increased from 7.45%to 52.31%(χ_(trend)^(2)=48.877,P<0.001).Multivariate analysis found that housework and unemployment(OR=1.623,95%CI:1.020-2.582),a previous history of adverse pregnancy(OR=1.682,95%CI:1.067-2.650),syphilis diagnosis in early or mid-term pregnancy(OR=2.688,95%CI:1.712-4.220),husband/sexual partner infected with syphilis(OR=2.993,95%CI:1.216-7.366)were risk factors for syphilis infected pregnant women for receiving treatment.The early or mid-term syphilis diagnosis in pregnancy(OR=4.464,95%CI:2.534-7.864),husband/sexual partner without syphilis(OR=2.982,95%CI:1.731-5.139)were protective factors for syphilis infected pregnant women to receive standardized treatment.Conclusions The treatment rate and standardized treatment rate of pregnant and lying-in women infected with syphilis in Urumqi City,shows an increasing trend year by year.The treatment rate has reached the national requirements,however there is still a gap between the standardized treatment rate and the national requirements.It is suggested that

关 键 词：妊娠梅毒 梅毒感染孕产妇 治疗 

分 类 号：R759.1[医药卫生—皮肤病学与性病学]